【焦真导师】招生“化学化工学院”研究生介绍

更新于 2025-03-19 导师主页
焦真 副教授 硕，博士生导师
男
化学化工学院
化学工程与技术
功能纳米材料创制,超临界流体技术,计算流体力学模拟
jiaozhen@seu.edu.cn

教育经历

1998-2002：南京大学化学化学学院，应用化学，本科

2002-2007：南京大学化学化工学院，物理化学，博士（硕博连续）

工作经历

2007.6-至今：东南大学化学化工学院，讲师，副教授

2015.1-至今：东南大学-蒙纳士大学苏州联合研究院

2024.9-至今：长三角医学先进技术创新中心，副主任

2017.9-2018.9：澳大利亚蒙纳士大学，访问学者

2013.3-2014.12：科学技术部基础研究管理中心，973计划和国家重大科学研究计划联络员


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科研项目

在研科研项目：

  1. 1. 国家自然科学基金重点项目，面向间歇缺氧致脑损伤诊治一体化的纳米磁基元脂质序构体材料，92163213，2022.1-2025.12，合作单位负责人
  2. 2. 国家重点研发计划课题，外场响应性磁基元及组装材料研究，2024YFF0508601，2024.12-2029.11，子课题负责人
  3. 3. 苏州市关键核心技术“揭榜挂帅”攻关项目，45-14nm制程的铜互连电镀设备关键技术研发，SYG202411，2024.11-2027.12，技术单位负责人
  4. 4. 江苏省重点研发计划产业前瞻与核心技术项目，基于微纳气泡强化的集成电路14nm先进制程单片清洗设备研发，BE2023066，2023.9-2026.9
  5. 5. 苏州市前沿技术研究项目，用于MPI成像的高性能铁基磁性纳米微球材料研发，SYG202318，2023.11-2026.12，技术单位负责人
  6. 6. 曹传欣校友发展研究基金，基于微气泡的气-液-固反应体系强化及其用于醇胺氧化耦合反应制备亚胺的研究，2023.7-2025.6，负责人
  7. 7. 苏州市产业前瞻与关键核心技术项目，面向药物递送的功能纳米磁基元脂质序构微球材料研发，SYC2022099，2022.11-2025.10，技术单位负责人
  8. 8. 苏州市产业前瞻与关键核心技术项目，面向集成电路28nm先进制程的单片清洗设备关键技术研发，SYC2022050，2022.11-2025.10，技术单位负责人


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研究成果

  1. 发表的论文：
  2. [43] Kailin Wang#, Mengnan Zhang#, Zejin Geng, Shuo Zhang, Zhuang Deng, Jin Tan, Qiang Zhang, Zhen Jiao*, Ning Gu*, One-Step Preparation of Magnetic Lipid Bubbles: Magnetothermal Effect Induces the Simultaneous Formation of Gas Nuclei and Self-Assembly of Phospholipids, ACS Applied Materials & Interfaces, 2024, 16, 30755-30765
  3. [42] Shuo Zhang, Zhuang Deng, Bingxu Yao, Jingyi Wu, Zhen Jiao*, Ning Gu*, Polyhedral Magnetic Nanoparticles of High Magnetization Synthesized by Hydrocooling and Magnetically Internal Heating Co-precipitation: Implications for Magnetic Resonance Imaging, Journal: ACS Applied Nano Materials, 2024, 7, 10377–10386
  4. [41] Jingyi Wu#, Qianqian Wang#, Zhuang Deng, Shuo Zhang, Zhen Jiao*, A Novel Design of Superparamagnetic Iron Oxide-based Metal-Organic Framework for SSI-assisted Drug Delivery System, New Journal of Chemistry, 2024, 48, 4118 - 4125
  5. [40] Zhen Jiao*, Zhuang Deng, Yi Zhang, Jinjing Wang, Fabrication Magnetic Composite Scaffolds with Multi-Modal Cell Structure for Enhanced Properties Using Supercritical CO2 Two-step Depressurization Foaming Process, Polymer Bulletin, 2024, 81: 5627–5652
  6. [39] Tao Du, Peng Zhang*, Zhen Jiao*, Jiancheng Zhou*, Yuxiao Ding*, Homogeneous and Heterogeneous Frustrated Lewis Pairs for the Activation and Transformation of CO2, Chemistry-A Asian Journal, 2024, e202400208
  7. [38] Zhen Jiao*, Shuo Zhang, Jinjing Wang, Yi Zhang, Preparation of magnetic scaffolds via supercritical carbon dioxide foaming process using iron oxide nanoparticles coated with CO2-philic materials as nucleating agents, Journal of Applied Polymer Science, 2024
  8. [37] Jingyi Wu#, Qianqian Wang#, Kailin Wang, Zejin Geng, Yadong Shao, Zhen Jiao*, Synthesis and characterization of Fe3O4@MIL-100 nanoparticles as an SSI-assisted drug carrier, Materials Letters, 2024, 137473
  9. [36] Zhuang Deng#, Yu Wang#, Shuo Zhang, Jingyi Wu, Shuning Wei, Zhen Jiao*, Ion-Doped Iron-Based Nanoparticles with Enhanced Magnetic Properties: Synthesis and Formation Mechanism via Coprecipitation, Journal of Magnetism and Magnetic Materials, 2024, 611, 172588
  10. [35] Qianqian Wang, Shuo Zhang, Zhuang Deng, Yi Zhang, Zhen Jiao*, Preparation of curcumol-loaded magnetic metal- organic framework using supercritical solution impregnation process, Microporous and Mesoporous Materials, 2023, 357, 112612
  11. [34] Ruan Nningjie, Jiao Zhen*,Tang Linglong, Response surface methodology to optimize supercritical carbon dioxide extraction of Polygonum Cuspidatum, Journal of AOAC international，2022, 105(1): 272–281
  12. [33] Wang Jinjing, Zhang Yi, Sun Jianfei*, Jiao Zhen*, Controllable fabrication of multi-modal porous PLGA scaffolds with different sizes of SPIONs using supercritical CO2 foaming, Journal of Applied Polymer Science, 2022, 139: e52287
  13. [32] Xu Qianrui, Gao Pengchao, Wang Yang, Jiang Wenjie, Wang Zhifei, Jiang Yong*, Jiao Zhen*, Using supercritical carbon dioxide to synthesize polymer nanospheres with an open hole on the surface and the application of spatially structured PS/P(DVB-co-MAA)@Fe3O4/TA@Ag nanocomposites, The Journal of Supercritical Fluids, 2022, 184, 105561.  
  14. [31] Zhang Yi, Wang Jinjing, Zhou Jiancheng, Sun Jianfei*, Jiao Zhen*, Multi-modal cell structure formation of poly (lactic-co-glycolic acid) /superparamagnetic iron oxide nanoparticles composite scaffolds by supercritical CO2 varying-temperature foaming, Polymers for Advanced Technologies, 2022, 33:1906–1915.
  15. [30] Jiao Zhen*, Zhang Mengnan, Yang Lixia, Wang Yuxuan, Fu Jiajie, Liquid−Liquid Equilibrium for the Ternary System Water + 1‑Methylimidazole + Ionic Liquid ([Hmim][PF6], [Omim][PF6], or [Omim][BF4]) at 303.15K, Journal of Chemical & Engineering Data, 2022, 67, 6, 1474–1480
  16. [29] Zhong Qiuwen#, Jiao Zhen#,*, Nie Wenhui, Li Yan, Gu Ning*, Numerical investigation of mass transfer behavior of a gas–liquid two‐phase Taylor flow in a microchannel by a volume‐of‐fluid multiphase flow system, International Journal of Mechanical System Dynamics, 2022, 2, 253–264
  17. [28] Wang Jiada#, Guo Ying#, Jiao Zhen*, Tan Jin. Zhang Mengnan, Zhang Qiang*, Gu Ning*, Generation of micro-nano bubbles by magneto induced internal heat for protecting cells from intermittent hypoxic damage, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 655, 130289
  18. [27] Yang L, Han Y, Jiao Z*, Measurement and Correlation of Liquid−Liquid Equilibria of Water (1) + 1‑Methylimidazole (2) + [Bmim][PF6] (3) Ternary Systems between 303.15 and 323.15 K, Journal of Chemical & Engineering Data, 2021, 66, 2134−2142
  19. [26] Han Y, Cheng J, Ruan N, Jiao Z*, Preparation of liposomes composed of supercritical carbon dioxide-philic phospholipids using the rapid expansion of supercritical solution process, Journal of Drug Delivery Science and Technology, 2021, 64, 102568
  20. [25] Jiao Z*, Ruan N, Wang W, Guo M, Han S, Cheng J, Supercritical carbon dioxide co-extraction of perilla seeds and perilla leaves: experiments and optimization, Separation Science and Technology, 2021, 56(3): 617-630
  21. [24] Jiao Z*, Han S, Wang W, Song J, Cheng J, Preparation and optimization of Vitamin E acetate liposomes using a modified RESS process combined with response surface methodology, Particulate Science and Technology,2020, 38(7): 863-875
  22. [23] Song J, Jiao Z*, Cheng J, Ruan N., Yang L, Synthesis of Supercritical Carbon Dioxide-philic Phospholipids and Determination of their Solubility, Polymer Engineering & Science, 2020, 60: 2333–2346
  23. [22] Jiao Z*, Han S, Wang W, Cheng J, Song J, Response surface optimization of catechin liposomes preparation using the rapid expansion of supercritical solution process, Journal of Nanoscience and Nanotechnology, 2020, 20(12): 7583-7592
  24. [21] Zha X, Han S, Wang W, Jiao Z*, Experimental measurement and correlation of solubility of ethosuximide in supercritical carbon dioxide, The Journal of Chemical Thermodynamics, 2019, 131: 104–110
  25. [20] Jiao Z*, Zha X, Wang Z, Wang X, Fan W, Response surface modeling of drug-loaded micelles preparation by supercritical carbon dioxide evaporation method using Box-Behnken experimental design, Journal of Nanoscience and Nanotechnology, 2019, 19(6): 3616-3620
  26. [19] Jiao Z*, Wang X, Han S, Zha X, Xia J, Preparation of vitamin C liposomes by rapid expansion of supercritical solution process: Experiments and optimization, Journal of Drug Delivery Science and Technology, 2019, 51, 1-6
  27. [18] Wang W, Han S, Zha X, Cheng J, Song J, Jiao Z*, Response Surface Optimization of Supercritical Carbon Dioxide Extraction of Tea Polyphenols from Green Tea Scraps, Journal of AOAC International，2019, 102(2), 451-456
  28. [17] Jiao Z*, Wang X, Yin Y, Xia J, Preparation and evaluation of vitamin C and folic acid co-loaded antioxidant liposomes, Particulate Science and Technology, 2019, 37(4), 449-455
  29. [16] Jiao Z*, Song J, Fan W, Wang X, Wang Z, Synthesis of poly (vinyl acetate) oligomer and their phase behavior in supercritical carbon dioxide, Journal of Southeast University(English Edition), 2019, 35(2) :264-268
  30. [15] Wang W, Han S, Jiao Z*, Cheng J, Song J, Antioxidant activity and total polyphenols content of camellia oil extracted by optimized supercritical carbon dioxide, Journal of the American Oil Chemists' Society, 2019, 96(11): 1275–1289
  31. [14] Jiao Z*, Cheng J, Guo M, Han S, Measurement and Correlation of Paeonol Solubility in Supercritical Carbon Dioxide, Journal of Chemical & Engineering Data, 2019, 64(10): 4424−4429
  32. [13] Jiao Z*, Fan W, Wang X, Wang Z, Synthesis of CO2-philic amphiphilic block copolymers by RAFT polymerization and its application on forming drug-loaded micelles using ScCO2 evaporation method, Journal of Drug Delivery Science and Technology, 2018,44:13-18
  33. [12]  Jiao Z*, Wang C, Yang Q, Wang X, Preparation and characterization of UV-curable urethane acrylate oligomers modified with cycloaliphatic epoxide resin，Journal of Coatings Technology and Research, 2018, 15(2): 251-258
  34. [11] Jiao Z*, Wang Z., Wang X., Fan W., Effects of Processing Parameters on the Properties of Amphiphilic Block Copolymer Micelles Prepared by Supercritical Carbon Dioxide Evaporation Method, Polish Journal of Chemical Technology, 2018， 20(1): 81-86.
  35. [10] Jiao Z*, Wang X, Yin Y, Wang Z, Mei Y, Xia J, Preparation and evaluation of a chitosan-coated antioxidant liposome containing vitamin C and folic acid, Journal of Microencapsulation, 2018, 35(3): 272-280.
  36. [9] Cheng J, Han S, Song Junying, Wang W, Jiao Z*, Solubility of Vitamin E Acetate in Supercritical Carbon Dioxide with Ethanol as Cosolvent, Journal of Chemical & Engineering Data, 2018, 63(11): 4248–4255
  37. [8] Wang X, Wang C, Zha X, Mei Y, Xia J, Jiao Z*, Supercritical carbon dioxide extraction of β-carotene and α-tocopherol from pumpkin :A Box-Behnken design for extraction variables, Analytical Methods, 2017, 9(2): 294-303
  38. [7] Jiao Z*, Wang X, Yang Q, Wang C, Modification and characterization of urethane acrylate oligomers used for UV-curable coatings, Polymer Bulletin, 2017， 74(7), 2497-2511
  39. [6] Jiao Z*, Yang Q, Wang X, Wang C, UV-curable hyperbranched urethane acrylate oligomers modified with different fatty acids, Polymer Bulletin, 2017，74(12), 5049-5063
  40. [4] Han S, Wang W, Jiao Z*; Wei X, Solubility of Vitamin E acetate in supercritical carbon dioxide: Measurement and Correlation. Journal of Chemical & Engineering Data, 2017, 62(11), 3854–3860
  41. [4] Jiao Z*, Sun Y, Yang Q, Wang X, Activity coefficients at infinite dilution of organic solutes in the ionic liquid ethyl(2-hydroxyethyl)dimethyl-ammonium diethylphosphate using gas–liquid chromatography, Fluid Phase Equilibria, 2012, 325: 15–19
  42. [3] Jiao Z, Liu N, Chen Z*, Selection suitable solvents to prepare paclitaxel-loaded micelles by solvent evaporation method, Pharmaceutical Development and Technology, 2012, 17(2): 164-169
  43. [2] Jiao Z, Wang X, Chen Z*, Folate-conjugated methoxy poly (ethylene glycol)/poly(L-Alanine) amphiphilic block copolymeric  micelles for targeted delivery of paclitaxel, Drug Delivery, 2011, 18(7): 478–484.
  44. [1] Jiao Z*, Chen Z, Wu Y, Ma S, Determination of Paclitaxel Solubility in Carbon Dioxide Using Quartz Crystal Microbalance, Chinese Journal of Chemical Engineering, 2011,19(2): 227-231
  45.  
  

  1. 专利:
  2. [16] 焦真，吴婧怡，一种用于二氧化碳光催化还原的光磁耦合反应装置，2024100874466
  3. [15] 焦真，王凯麟，顾宁，一种测定微纳气泡溶液中气泡含气量的方法, 2024100938260
  4. [14] 焦真，邓壮，崔婧璇，一种磁性微气泡催化剂及其在醇胺耦合氧化反应中的应用，202410614594.9
  5. [13] 焦真，韦淑宁，董歌，施晶晶，一种基于共沉淀法制备磁性纳米颗粒的装置和方法，202411145100.3
  6. [12] 焦真，张硕，顾宁，张梦楠，陈怡，一种磁性脂质微纳气泡的连续制备装置及方法，202211229704.7
  7. [11] 焦真，张梦楠，顾宁，杨芳，孙剑飞，陈怡，一种基于磁热效应诱导界面自组装制备磁性脂质气泡的方法，ZL202110606441.6
  8. [10] 焦真， 王倩倩，李乃旭，顾宁，一种基于超临界浸渍制备磁性MOF载药系统的方法，ZL202210458332.9
  9. [9] 焦真，王甲妲，顾宁，孙剑飞，陈怡，一种微纳气泡的制备方法，ZL 202010912586.4
  10. [8] 焦真，张溢，孙剑飞，周建成，一种利用超临界流体发泡技术制备骨组织工程支架的方法，ZL202010155938.6
  11. [7] 焦真，王卫芳，程江瑞，宋俊颖，韩赛，一种改进的超临界抗溶剂法制备聚合物载药颗粒装置，ZL 201810554543.6
  12. [6] 焦真，阚道琴，李乃旭，马全红，周建成，一种基于Radziszewski反应法制备的简单咪唑类化合物的分离工艺，ZL 201910348491.1
  13. [5] 焦真，宋俊颖，程江瑞，韩赛，王卫芳，查贤君, 一种具有亲超临界二氧化碳性能的合成磷脂及其制备方法, ZL 201810337209.5
  14. [4] 焦真，樊文景，王梓屹，王秀东；一种两亲嵌段聚合物及其制备方法；ZL 201510121569.8
  15. [3] 焦真，王秀东，王梓屹，查闲君，王晨，殷玉婷；一种从天然物中提取营养素并制剂的系统，ZL 201610072488.8
  16. [2] 焦真，王晨晨，杨前前，王献伟；脂环族环氧聚氨酯丙烯酸酯紫外光固化涂料及其制备方法；ZL 201410212211.1
  17. [1] 焦真，樊文景，王秀东，王梓屹；天然物中脂性药物的超临界萃取/胶束化一体装置；ZL 201510186337.0


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