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东南大学生命科学与医学工程院副研究员,博士生导师。主要从事合成生物、系统生物学、生物医用材料等领域的研究。以第一作者、通讯作者在Nanoscale、 ACS Applied Materials &Interfaces、Biotechnology for Biofuel、ACS Chemical Biology、Proteomics等杂志发表SCI论文24篇,累计影响因子近80。发表文章总引用次数500多次,单篇引用次数达110次。主持国家自然科学基金2项,东南大学校级项目3项,参与973、863等重大科技项目多项。
目前的主要研究方向有(1)真菌产纤维素酶机理研究、基因工程改造及其应用;(2)抗菌抗癌纳米材料研发;(4)天然产物的开发应用。
工作教育经历:
2014/9-至今, 东南大学, 生医学院, 副教授
2011/9-2014/8, 美国密歇根大学,化工系和化学系,博士后
2005/9-2011/6,天津大学, 制药工程, 博士,元英进 。
2009/9-2011/6,美国密歇根大学,化学工程系, 联合培养 Xiaoxia Nina Lin。
2001/9-2005/9,天津大学,制药工程, 学士。
(1)微生物转录水平调控机理研究
(2)真菌非经典分泌途径的研究
(3)碳点的合成和应用
(4)抗菌抗癌纳米药物研发
(1) Ai-Ping Pang,Funing Zhang, Xin Hu, Yongsheng Luo, Haiyan Wang, Samran Durrani, Fu-Gen Wu,Bing-Zhi Li, Zhihua Zhou, Zuhong Lu*, Fengming Lin*. Glutamineinvolvement in nitrogen regulation of cellulase production in fungi.Biotechnology for Biofuels, 2021, 14:199. (IF: 6.0;1区)
(2) Ai-Ping Pang,Haiyan Wang, Funing Zhang, Xin Hu, Fu-Gen Wu, Zhihua Zhou, Wei Wang, Zuhong Lu*,Fengming Lin*. High-dose rapamycin exerts a temporary impact on T.reesei RUT-C30 through gene trFKBP12. Biotechnology for Biofuels, 2021,14:77. (IF: 6.0; 1区)
(3) Ai-Ping Pang,Haiyan Wang, Yongsheng Luo, Zihuayuan Yang, Zhiyu Liu, Zhao Wang, Bingzhi Li,Song Yang, Zhihua Zhou, Xiaolin Lu, Fu-Gen Wu, Zuhong Lu*, Fengming Lin*.Dissecting cellular function and distribution of β-glucosidases in Trichodermareesei. mBio, 2021, 12(3):e03671-20. (IF:7.8; 1区)
(4) Fengming Lin, Qiu-Yi Duan, and Fu-Gen Wu*.Conjugated Polymer-Based Photothermal Therapy for Killing Microorganisms. ACS Applied PolymerMaterials, 2020, 2, 4331−4344 .(IF: 4.1; 2区)
(5) ZihuayuanYang, Ying Qiao, Junying Li, Fu-Gen Wu, FengmingLin*. Novel Water-Soluble Photosensitizer from Trichoderma reeseifor photodynamic inactivation of gram-positive bacteria. Langmuir 2020,36, 44, 13227–13235. (IF: 3.9; 2区)
(6) Liang Ma, Ai‑PingPang, Yongsheng Luo, Xiaolin Lu* and Fengming Lin*. Beneficialfactors for biomineralization by ureolyticbacterium Sporosarcina pasteurii. Microbial Cell Factory, 2020,19:12. (IF: 5.3; 2区)
(7) ChengchengLi, Ai-Ping Pang, Hang Yang, Rongjin Lv, Zhihua Zhou, Fu-Gen Wu, FengmingLin*. Tracking localization and secretion of cellulase spatiotemporally anddirectly in living Trichoderma reesei. Biotechnology for biofuels, 2019,12,200. (IF: 6.0; 1区)
(8) Fengming Lin, Hao-Ran Jia, and Fu-Gen Wu. Glycol chitosan: Awater-soluble polymer for cell imaging and drug delivery. Molecules 24.23(2019): 4371. (IF: 4.4; 3区)
(9) Fengming Lin, Yan-Wen Bao, and Fu-Gen Wu. Carbon Dots for Sensing and Killing Microorganisms.C-Journal of Carbon Research, 2019, 5: 33.
(10) Chengcheng Li, FengmingLin*, Wei Sun, Shaoxun Yuan, Zhihua Zhou, Fu‑Gen Wu and Zhan Chen.Constitutive hyperproduction of sorbicillinoids in Trichoderma reesei ZC121.Biotechnology for Biofuels, 2018, 11:291.(IF:6.0; 2区)
(11)Fengming Lin, Yan-Wen Bao and Fu-Gen Wu. Improving thePhototherapeutic Efficiencies of Molecular and Nanoscale Materials by TargetingMitochondria. Molecules, 2018, 23, 3016. (IF: 4.4; 3区)
(12)Fengming Lin*, Chengcheng Li, and Zhan Chen.Exopolysaccharide-Derived Carbon Dots for Microbial Viability Assessment.Frontiers in Microbiology. 2018, 9. 2697. (IF: 5.6; 2区)
(13)Chengcheng Li, Fengming Lin*,Wei Sun, Fu-Gen Wu, Hang Yang, Roujing Lv, Ya-Xuan Zhu, Hao-Ran Jia, Chu Wang,Ge Gao, and Zhan Chen. Self-assembled rose bengal-exopolysaccharidenanoparticles for improved photodynamic inactivation of bacteria by enhancingsinglet oxygen generation directly in the solution. ACS Applied Materials &Interfaces, 2018, 10(19), 16715-16722 (IF:9.2; 1区)
(14)Fengming Lin*, Chengcheng Li, Zhan Chen. Bacteria-derivedcarbon dots inhibit biofilm formation of Escherichia coli without affectingcell growth. 2018, Frontiers in Microbiology, 2018, 9, 259. (IF: 5.6; 2区)
(15) Chengcheng Li,Fengming Lin*, Le Zhou, Lei Qin, Bingzhi Li, Zhihua Zhou,Mingjie Jin, Zhan Chen. Cellulase hyper-production by Trichoderma reesei mutantSEU-7 on lactose. Biotechnology for Biofuels, 2017,10, 228. (IF: 6.0; 2区)
(16) Fengming Lin *, Chengcheng Li, Li Dong, Degang Fu,and Zhan Chen*. Imagingbiofilm-encased microorganisms using carbon dots derived from L. plantarum.Nanoscale,2017, 9, 9056-9064. (IF: 7.8; 1区)
(17) Chengcheng Li, Le Zhou, Hang Yang, Roujing Lv,Peilong Tian, Xu Li, Yaqin Zhang, Zhan Chen*, Fengming Lin*. Self-assembled ExopolysaccharideNanoparticles for Bioremediation and Green Synthesis of Noble MetalNanoparticles. ACSApplied Materials & Interfaces, 2017,9, 22808−22818. (IF: 9.2; 1区).
(18) Chengcheng Li, FengmingLin*, Yizhen Li, Wei Wei, Hongyin Wang, Lei Qin, Zhihua Zhou, BingzhiLi, Fugen Wu, Zhan Chen, A beta-glucosidase hyper-production Trichoderma reeseimutant reveals a potential role of cel3D in cellulose production. MicrobialCell Factories,2016,15(1):151. (IF:5.3; 2区)
(19) Fengming Lin, Kyle L. Fergusion, David R. Boyer, Xiaoxia NinaLin, E. Neil G. Marsh.Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactorrequired by Ferulic Acid Decarboxylase and 4-Hydroxy-3-polyprenylbenzoic AcidDecarboxylase. ACSChemical Biology, 2015, 10, 1137-1144. (IF: 5.09; 2区)
(20) Fengming Lin, E. Neil G. Marsh, Xiaoxia Nina Lin. Recent progress in hydrocarbon biofuelsynthesis: pathways and enzymes. Chinese Chemical Letters,2015, 26, 431-434. (IF: 6.8;2区)
(21) Fengming Lin, Yu Chen, Robert Levine, Kilho Lee, Yingjin Yuan,Xiaoxia Nina Lin. Improvingfatty acid availability for bio-hydrocarbon production in Escherichia coli by metabolic engineering. PLoSOne, 2013, 8(10): e78595. (IF: 3.2; 3区)
(22) Fengming Lin, Debasis Das, Xiaoxia Nina Lin, E. Neil G. Marsh. Aldehyde-forming fatty acyl-CoA reductase fromcyanobacteria: expression, purification and characterization of the recombinantenzyme. FEBS Journal,2013, 280:4773-4781. (IF:5.5; 2区)
(23) Fengming Lin, Ying Tan,Ying-jin Yuan. Temperalquantitative proteomics of Saccharomycescerevisiae in response to a nonlethal concentration of furfural.Proteomics,2009, 9:5471-5483. (IF:4.0; 2区)
(24) Fengming Lin, Bin Qiao,Ying-jin Yuan.Comparative proteomic analysis of tolerance and adaptation of ethanologenic Saccharomyces cerevisiae to furfural,a lignocellulosic inhibitory compound. Appliedand Environmental Microbiology, 2009, 75(1):3765-3776.(IF:4.8; 2区)
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