[1].       中国博士后科学基金项目：“双链DNA芯片的研制及在DNA结合蛋白研究中的应用” 2001年（第二十八批博士后科学基金资助金）；经费1万元；项目负责人。

[2].       国家自然科学基金项目（No.60201005）：“点突变双链DNA芯片的研制及在DNA结合蛋白研究中的应用” ；2002-2003；经费7万元；项目负责人。

[3].       国家高技术研究发展计划(863计划)项目一级子课题（2003AA2Z2001）：“运用双链微阵列芯片研究中药作用机理”；2003-2005；经费90万元；课题负责人。

[4].       国家自然科学基金重大研究计划项目（No.90408027）：“转录因子蛋白检测DNA微阵列芯片研制及应用研究”；2004-2006；经费30万元；项目负责人。

[5].       国家自然科学基金项目（No.60471019）：“双链DNA微阵列芯片研制及应用研究”；2004-2006；经费23万元；项目负责人。

[6].       江苏省高技术研究计划项目（No.BG2006037）：“运用dsDNA-Plate筛选NF-B活性抑制药物分子”；2006-2008；经费30万元；项目负责人。

[7].       国家重大科学研究计划项目一级课题（No.2006CB933205）： “纳米颗粒对细胞内基因表达调控的作用及机制研究”；2006-2010；经费160万元；课题负责人。

[8].      国家自然科学基金项目（No.60871014）：“用dsDNA微阵列芯片筛选NF-κB DNA靶点及靶基因”；2009-2011；经费35万元；项目负责人。

[9].      科技部国际科技合作项目（No.2009DFA31990）：“用于细胞操控和分析的功能纳米结构及纳米器件”；2009-2011；经费100万元；项目负责人。

[10].    教育部新世纪优秀人才支持计划项目（No.NCET-08-0110）：“dsDNA 微阵列芯片结合生物信息学筛选NF-κBDNA 靶点及靶基因”； 2009-2011；经费50万元；项目负责人。

[11].    农业部转基因生物新品种培育重大专项项目（No. 2009ZX08008-007B）一级课题：“中原转基因肉用山羊育种新材料研制”；2009-2010；经费80万元；一级课题负责人。

[12].    国家自然科学基金项目（No.61171030）：“转录因子DNA结合谱绘制新方法及其应用研究”；2012-2015；经费60万元；项目负责人。

[13].    江苏省社会发展项目（BE2012741）“肝炎、肝癌靶向NF-κB siRNA高通量筛选及磁性纳米载体制剂研究” ；2012-2015；经费25万元；项目负责人。

[14].    国家自然科学基金项目（No. 61571119）：“细胞内转录因子高分辨率DNA结合靶点鉴定新技术的发展及其应用研究”；2016-2019；经费65万元；项目负责人。

[15].    国家重点研发计划：项目“铁基纳米材料类酶效应与急性髓系白血病诊疗技术（No. 2017YFA0205500）”；课题2：“铁基纳米酶调控细胞氧化-还原环境与白血病耐药（No.2017YFA0205502）”；2017-2022；经费100万元；课题主要PI。参加

[16].    国家自然科学基金项目（No. 61971122）：“基于CRISPR的基因调控元件及调控因子鉴定新技术”； 2020-2023；经费65万元；项目负责人。

[17].    江苏省重点研发计划项目（No. BE2018713）：“基于CRISPR基因编辑技术的HPV分型快速诊断建立及临床应用”； 2018-2021；经费50万元；课题主要PI。参加

专著：

[1].        《真核生物转录调控：概念、策略与技术》（Transcriptional Regulation in Eukaryotes-Concepts, Strategies andTechniques. eds. Michael F. Carey, Craig L. Peterson, Stephen T. Smale. ColdSpring Harbor Laboratory Press; 2nd edition. 2009）。王进科主译（100万字），科学出版社。2012，6。ISBN978-7-03-034615-5。

[2].        《生物医学实验》。王进科 编著（71万字）。科学出版社。2013，6。教育部生物医学工程专业教学指导委员会推荐教材。ISBN978-7-03-037939-9。

[3].        Jinke Wang，Zuhong Lu. Fabrication ofDouble-stranded DNA Microarray on Solid Surface for Studying DNA-proteinInteractions. In: The Frontiers ofBiochip Technology. eds. Xing, WL and Cheng, J. , Kluwer AcademicPublishers, New York, U.S.A., 2005. pp246-273

[4].        JinkeWang*, Yingxun Liu, Yong Hou, Zhongpin Chen, Ning Gu. NIRF labeling of ironnanoparticles and applications in cell labeling and in vivo imaging. In: Nanoparticles in Biology and Medicine. eds. Mikhail Soloviev. 2012, Chapter 17,pp221-237. Springer.

[5].        赵志坤,王进科,侯勇.功能纳米材料及结构对细胞遗传特性的影响。生物医用纳米材料对细胞的作用；顾宁，许海燕等编著，科学出版社，2014.

第一作者SCI论文：

[1].       Tong Xiang Li#, JinKe Wang#, YunFei Bai, ZuHong Lu*. Anovel method for screening the species-specific gDNA probes for speciesidentification. Nucleic Acids Research 2004, 32 (4): e45 (# the joint firstauthor)   IF8.278

[2].       Jinke Wang*, Tongxiang Li, Xiaoying Guo and Zuhong Lu. Exonuclease IIIprotection assay with FRET probe for detecting DNA-binding proteins. NucleicAcids Research 2005, 33(2): e23 (*correspondence author).  IF8.278

[3].       Jinke Wang, Yunfei Bai, Tongxiang Li, Zuhong Lu. DNA microarrays withunimolecular hairpin double-stranded DNA probes: Fabrication and exploration ofsequence-specific DNA-protein interactions. Journal of Biochemical andBiophysical Methods (Journal ofproteomics) 2003, 55: 215-232. IF4.302

[4].       Jin K. Wang, Tong X. Li, Zu H. Lu. A Method for Fabricating Uni-dsDNAMicroarray Chip for Analyzing DNA-binding Proteins. Journal of Biochemical andBiophysical Methods (Journal ofproteomics) 2005, 63(2):100-110.  IF4.302

[5].       Jinke Wang, Jie Lu, GuangmingGu and Yingxun Liu. In vitro DNA-binding profile of transcription factors:methods and new insights. Journal of Endocrinology, 2011, 210: 15-27. IF4.058

[6].       Jin K. Wang, Tong X. Li, Yun F. Bai, Zu H. Lu. Evaluating the bindingaffinities of NF-kappaB p50 homodimer to the wild-type and single-nucleotidemutant Ig-kappaB sites by the unimolecular dsDNA microarray. AnalyticalBiochemistry 2003, 316: 192-201. IF2.582

[7].       Jinke Wang, Tongxiang Li, Yunfei Bai, Yi Zhu, Zuhong Lu. FabricatingUnimolecular Double-stranded DNA Microarray on solid surface for probingDNA-protein/drugs Interactions. Molecules 2003, 8: 153-168. IF2.428

[8].       Jin K. Wang*, Jian L. Li, Min L. Li, Dong Hua, Hong M. Chen. Assay ofDNA-binding proteins with a dsDNA-coupled plate. Clinical Biochemistry 2006, 39(2):167-175.(*correspondence author)  IF2.45

[9].       JinKe Wang*, Min L. Li, Dong Hua, and Qixin Chen. Exonuclease-mediatedELISA-like assay for detecting DNA-binding activity of transcription factors:measurement of activated NF-κB. BioTechniques 2006, 41(1): 79-89.(*correspondence author)  IF2.399

[10].     J. Wang & D. Xia.Studies on Fish heterosis with DNA fingerprinting. Aquaculture Research, 2002, 33:941-947. IF1.422

通讯作者SCI论文：

[1].       Jianlin Li, Hongmei Chen, Minli Li, Dong Hua, Zuhong Lu, Jinke Wang*. Anoptimized assay for transcription factor NF-κB with dsDNA-coupled Microplate, Colloidsand Surfaces B: Biointerfaces 2006, 55(1):31-37. IF3.554

[2].       Shen S, Liu Y, Huang P, Wang J*. In vitro cellular uptake and effects ofFe3O4 magnetic nanoparticles on HeLa cells. J NanosciNanotechnol. 2009, 9(5): 2866-71. IF1.149

[3].       Yingxun Liu, Zhongping Chen, Ning Gu, Jinke Wang*. Effects of DMSA-coatedFe3O4 magnetic nanoparticles on global gene expression ofmouse macrophage RAW264.7 cells. Toxicology Letters 2011, 205: 130-139.  IF3.145

[4].       Yingxun Liu, Zhongping Chen, Jinke Wang*. Systematic evaluation ofbiocompatibility of magnetic Fe3O4 nanoparticles with sixdifferent mammalian cell lines. J Nanopart Res 2011, 13: 199–212. IF2.175

[5].       Yingxun Liu, Jinke Wang*. Comparative and quantitative investigation ofcell labeling of a 12-nm DMSA-coated Fe3O4 magneticnanoparticle with multiple mammalian cell lines. J. Mater. Res., 2011, 26 (6):822-831. IF1.713

[6].       Yingxun Liu and Jinke Wang*. Effects of Fe3O4 Nanoparticleson the Transcription of Genes with Iron-responsive Elements. 2012 12th IEEEInternational Conference on Nanotechnology (IEEE-NANO). The InternationalConference Centre Birmingham. 20-23 August 2012, Birmingham, United Kingdom. SCI收录

[7].       Fei Zhou, Yujun Xing, Xinhui Xu, Yang Yang, Jinwei Zhang, Zhengliang Ma,Jinke Wang*. NBPF is a potential DNA-binding transcription factor that isdirectly regulated by NF-κB. Inter J Biochem Cell Biol, 2013, 45:2479-2490. IF4.152

[8].       Yingxun Liu, Jinke Wang*. Effects of DMSA-coated Fe3O4nanoparticle on the transcriptions of genes related to iron and osmosishomeostasis. Toxicological Science, 2013, 131(2): 521-536. IF4.328

[9].       Guangming Gu, Tingting Wang, Yang Yang, Hinxin Xu, Jinke Wang*. Animproved SELEX-Seq strategy for characterizing DNA-binding specificity oftranscription factor: NF-κB as an example. Plos ONE, 2013, 8(10): e76109. IF3.534

[10].     Yujun Xing, Fei Zhou, JinkeWang*. Subset of genes targeted by transcription factor NF-κB inTNFα-stimulated human HeLa cells. Functional & Integrative Genomics, 2013,13:143-154. IF3.292

[11].     Ying Chen, Jinke Wang*. A membrane-basednear-infrared fluorescence assay for detecting DNA methylation and transcription.Anal Biochem, 2013, 442:196-204. IF2.582

[12].     Yujun Xing, Yang Yang, FeiZhou, Jinke Wang*. Characterization of genome-wide binding of NF-κB RelA inTNFα-stimulated HeLa cells and its effect on gene expression. Gene, 2013, 526:142-149.IF2.196

[13].     Guo Wei, Ling Xiao-Qian,Hua Wen-Yu, Wang Jin-Ke*.Cloning of GH, IGF-I and SST genes of Anhui white goatfor transgenic application. Journal of Animal and Veterinary Advances. 2013, 12(3):259-302. IF0.365

[14].     Yingxun Liu, Jinglu Zou,Xin Wang, Tingting Wang and Jinke Wang. Effects of 2,3-DimercaptosuccinicAcid-Coated Fe3O4 Nanoparticles on Genes in Two MouseCell Lines. Journal of Biomedical Nanotechnology, 2014, 10 (8), 1574-1587.  IF7.578

[15].     Fei Zhou, Wei Wang, YujunXing, Tingting Wang, Xinhui Xu, Jinke Wang*. NF-κB target microRNAs and theirtarget genes in TNFα-stimulated HeLa Cells. Biochim Biophys Acta-Gene RegulatoryMechanisms, 2014,1839(4): 344-354.  IF5.44

[16].     Junhuan Yin, Ping Gan, FeiZhou, Jinke Wang*. SensitiveDetection of Transcription Factors Using Near-Infrared Fluorescent Solid-PhaseRolling Circle Amplification. Anal Chem. 2014,86(5):2572-2579.  IF5.825

[17].     Ying Chen, Yan Pan, BeibeiZhang, Jinke Wang*. Analyzing abundance of mRNA molecules with a near-infraredfluorescence technique. Anal Bioanal. Chem. 2014, 406(2):537-548. IF3.578

[18].     Du W, Gao J, Wang T, WangJ. Single-Nucleotide Mutation Matrix: A New Model for Predicting the NF-κB DNABinding Sites. PLoS ONE, 2014, 9(7): e101490. IF3.534

[19].     Fei Zhou, Xiaoqian Ling, JunhuanYin, Jinke Wang*. Analyzing transcription factor activity using near infraredfluorescent bridge polymerase chain reaction. Anal Biochem, 2014, 448:105-112. IF2.305

[20].     Jinglu Zou, Xin Wang, LingZhang, Jinke Wang*. Iron nanoparticles significantly affect the in vitro and invivo expression of Id genes. Chemical Research in Toxicology, 2015, 28(3):373-383.IF3.025

[21].     Lin Zhang, Xin Wang, JingluZou, Yingxun Liu, Jinke Wang. Effects of an 11-nm DMSA-coated iron nanoparticleon the gene expression profile of two human cell lines, THP-1 and HepG2. Journalof Nanobiotechnology, 2015, 13:3. IF4.23

[22].     Lin Zhang, Xin Wang, JingluZou, Yingxun Liu, Jinke Wang*. DMSA-coated iron oxide nanoparticle greatlyaffect the expression of genes coding cysteine-rich proteins by its DMSAcoating. Chemical Research in Toxicology, 2015, 28(10):1961-1974.  IF3.025

[23].     Yang Yang, Jian Wu, JinkeWang. A database and functional annotation of NF-κB target genes. Int J ClinExp Med 2016;9(5):7986-7995  SCI

[24].     Y. YANG, J.-K. WANG. Thefunctional analysis of MicroRNAs involved in NF-κB signaling. European Reviewfor Medical and Pharmacological Sciences. 2016; 20: 1764-1774   SCI

[25].     He DX, Gu F, Wu J, Gu XT, Lu CX, Mao AQ, Zhang GY, Ding ZY, Wang JK, Hao JJ, Fu L, Ma X. TargetingPSG1 to enhance chemotherapeutic efficacy: new application for anti-coagulantthe dicumarol. Clin Sci (Lond). 2016;130(24):2267-2276. SCI

[26].     Ying Chen, Qian Sun, Jinke Wang. A microwell-based near-infraredfluorescence assay of DNA methylation. Transl Cancer Res 2017, 6(1):117-128. doi:10.21037/tcr.2017.01.40

[27].    Zhou F, Xu X, Wang D, Wu J, Wang J.Identification of novel NF-κB transcriptional targets in TNFα-treated HeLa andHepG2 cells. Cell Biol Int. 2017May;41(5):555-569. doi: 10.1002/cbin.10762.

[28].    Zhou F, Xu X1, Wu J, Wang D, Wang J.NF-κB controls four genes encoding core enzymes of tricarboxylic acid cycle. Gene. 2017Jul 20;621:12-20. doi: 10.1016/j.gene.2017.04.012.

[29].    Dai W, Wu J, Zhang S, Shi B, Xu X, Wang D, Wang J.Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2. Int J BiochemCell Biol. 2017 Aug;89:157-170. doi: 10.1016/j.biocel.2017.05.031.

[30].    Xu X, Zhang B, Gan P, Wu J, Dai W, Zhang L, Wang J.On-nylon membrane detection of nucleic acid molecules by rolling circleamplification. Anal Biochem. 2017 Sep 15;533:26-33.doi: 10.1016/j.ab.2017.06.005.

[31].    Hongmei Xie, Ling Zhang, LinWu, and Jinke Wang. Polyacrylamide Nanoparticles with Visible and Near-InfraredAutofluorescence. Part. Part. Syst. Charact. 2017, 34, 1700222

[32].    Ling Zhang, Yan Chen, Lin Wu,Yingxun Liu, and Jinke Wang. Effects of Iron Nanoparticles on Immune Responseof Two Immunocytes Like Virus. Nanosci. Nanotechnol. Lett. 2017, 9, 1934–1946(2017)  IF1.889

[33].    Wang D, Dai W, Wu J, Wang J.Improving transcriptional activity of human cytomegalovirus major immediate-earlypromoter by mutating NF-κB binding sites. Protein Expr Purif. 2018Feb;142:16-24. doi: 10.1016/j.pep.2017.09.008.

[34].    Wang D, Tang H, XuX, Dai W, Wu J, Wang J. Control the intracellular NF-κB activityby a sensor consisting of miRNA and decoy. Int J BiochemCell Biol. 2018, Volume 95, February 2018, Pages 43–52. doi:10.1016/j.biocel.2017.12.009.

[35].    BeibeiZhang, Qiao Wang, Jian Wu, Yin Chen, and Jinke Wang. Detectionof nucleic acids with a novel stem-loop primer rolling circle amplificationtechnique. BioTechniques, Vol. 64, No. 2, February 2018, pp. 69–80.

[36].    ZhangB, Wang Q, Xu X, Xia Q, Long F, Li W, ShuiY, Xia X, Wang J. Detection of target DNA with a novelCas9/sgRNAs-associated reverse PCR (CARP) technique. Anal BioanalChem. 2018 May; 410(12):2889-2900. doi: 10.1007/s00216-018-0873-5. Epub2018 Mar 15.

[37].    Zhang B, Xia Q, WangQ, Xia X, Wang J. Detecting and typing target DNA with a novelCRISPR-typing PCR (ctPCR) technique. Anal Biochem. 2018 Sep19;561-562:37-46. doi: 10.1016/j.ab.2018.09.012.

[38].     Jian Wu, Wei Dai, Lin Wu and JinkeWang. SALP, a new single-stranded DNA library preparation method especiallyuseful for the high-throughput characterization of chromatin openness states.BMC Genomics (2018) 19:143. https://doi.org/10.1186/s12864-018-4530-3

[39].    JianWu, QiaoWang, Wei Dai,Wei Wang, MingYue, Jinke Wang. Massive GGAAs in genomic repetitivesequences serve as a nuclear reservoir of NF-κB. Journal of Genetics andGenomics, Volume 45, Issue 4, 20 April 2018, Pages 193-203.

[40].    WangQ, Zhang B, Xu X, Long F, Wang J. CRISPR-typing PCR(ctPCR), a new Cas9-based DNA detection method. Sci Rep. 2018 Sep20;8(1):14126. doi: 10.1038/s41598-018-32329-x.

[41].    WangD, Dai W, Wang J. A Cell-Specific Nuclear Factor-Kappa B-ActivatingGene Expression Strategy for Delivering Cancer Immunotherapy. Hum GeneTher. 2019 Apr;30(4):471-484. doi: 10.1089/hum.2018.093. Epub 2018 Nov 15.

[42].    DaiW, Xu X, Wang D, Wu J, Wang J.Cancer therapy witha CRISPR-assisted telomerase-activating gene expression system.Oncogene. 2019 May; 38(21): 4110-4124. doi: 10.1038/s41388-019-0707-8.Epub 2019 Jan 29.

[43].    WuJ, Dai W, Wu L, Li W, Xia X, Wang J. Decoding geneticand epigenetic information embedded in cell free DNA with adapted SALP-seq. IntJ Cancer. 2019 Nov 1;145(9):2395-2406. doi: 10.1002/ijc.32206. Epub 2019Feb 27.

[44].    ZhangS, Chen H, Wang J, Generate TALE/TALEN easily and rapidly as generating CRISPR,Molecular Therapy: Methods & Clinical Development (2019), 2019 Feb19;13:310-320. doi: 10.1016/j.omtm.2019.02.004. eCollection 2019 Jun 14..

[45].    ZhangL, Tan S, Liu Y, Xie H, Luo B, Wang J. In vitroinhibition of tumor growth by low-dose iron oxide nanoparticles activatingmacrophages. J Biomater Appl. 2019 Feb;33(7):935-945. doi:10.1177/0885328218817939.

[46].    Xu X, Gao J, Dai W, Wang D, Wu J, Wang J. Gene activation by aCRISPR-assisted trans enhancer. Elife. 2019Apr 11;8. pii: e45973. doi: 10.7554/eLife.45973.

[47].    Dai W, Wu J, Wang D, Wang J*. Cancer gene therapy by NF-κB-activated cancercell-specific expression of CRISPR/Cas9 targeting telomeres. Gene Ther.2020; 27(6):266-280. doi:10.1038/s41434-020-0128-x

[48].    Wang J, Zhang S, Xu X, Xing Y,Li Z, Wang J*. Fast DNA Extraction withPolyacrylamide Microspheres for Polymerase Chain Reaction Detection. ACSOmega. 2020;5(23):13829-13839. Published 2020 Jun 4.doi:10.1021/acsomega.0c01181

[49].    Zhang S, Wang J, Wang J*. One-Day TALEN Assembly Protocol and aDual-Tagging System for Genome Editing. ACSOmega. 2020 Jul 29; 5(31):19702-19714. Doi: 10.1021/acsomega.0c02396. PMID:32803065; PMCID: PMC7424704.

[50].    Liu S, Wu J, Xia Q, Liu H, LiW, Xia X, Wang J*. Finding new cancerepigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq andmachine learning. Comput Struct Biotechnol J. 2020 Jul 7; 18:1891-1903. Doi:10.1016/j.csbj.2020.06.042. PMID: 32774784; PMCID: PMC7387736.

[51].    Jinliang Gao, Tao Luo, Na Lin,Shuyan Zhang, Jinke Wang*. A New Tool for CRISPR-Cas13a-Based Cancer GeneTherapy. Molecular Therapy-Oncolytics, Volume 19, 2020, Pages 79-92, ISSN2372-7705,https://doi.org/10.1016/j.omto.2020.09.004.

[52].    Luo T, Gao J, Lin N, Wang J*. Effects of TwoKinds of Iron Nanoparticles as Reactive Oxygen Species Inducer and Scavenger onthe Transcriptomic Profiles of Two Human Leukemia Cells with DifferentStemness. Nanomaterials (Basel). 2020 Sep 30;10(10):1951. doi:10.3390/nano10101951. PMID: 33007950; PMCID: PMC7600526.

[53].    ShicaiLiu, Hailin Tang, Hongde Liu, Jinke Wang*. Multi-label Learningfor Diagnosis of Cancer and Identification of Novel Biomarkers withHigh-Throughput Omics. Current Bioinformatics, 2021，16（2）：261- 273 ；DOI: 10.2174/1574893615999200623130416.(E-pub Ahead of Print)

[54].    Zhou F, Li Y, Huang Y, Wu J, WuQ, Zhu H, Wang J. Upregulation of CASP9 through NF-κB and ItsTarget MiR-1276 Contributed to TNFα-promoted Apoptosis of Cancer Cells Inducedby Doxorubicin. Int J Mol Sci. 2020 Mar 26;21(7):2290. doi:10.3390/ijms21072290. PMID: 32225068; PMCID: PMC7177739.

[55].    Xu X, Luo T, Gao J, Lin N, LiW, Xia X, Wang J*. CRISPR-Assisted DNADetection: A Novel dCas9-Based DNA Detection Technique. CRISPR J. 2020Dec;3(6):487-502. doi: 10.1089/crispr.2020.0041. PMID: 33346711.

[56].    Gao J, Wu L, Yang D, Gong W,Wang J*. A One-Pot CRISPR/Cas9-Typing PCR forDNA Detection and Genotyping. J Mol Diagn. 2021, Jan, 23(1):46-60. doi:10.1016/j.jmoldx.2020.10.004.

[57].    Gao J, Luo T, Wang J. Geneinterfered-ferroptosis therapy for cancers. Nat Commun. 2021 Sep 7;12(1):5311.doi: 10.1038/s41467-021-25632-1. PMID: 34493724; PMCID: PMC8423858.

[1].     一种端粒酶启动基因表达方法及其应用；申请日：2017-03-28；ZL201710191647.0；发明人：王进科、戴薇、徐新慧；授权日：2020-07-31；

[2].     一种自荧光聚丙烯酰胺纳米粒子及其制备方法和应用；申请日：2017-08-28；ZL201710748790.5；发明人：王进科、谢红梅；授权日：2020-03-03；

[3].     一种真核启动子及其制备方法和应用；申请日：2017-09-20；ZL201710849944.X；发明人：王进科、王丹阳；授权日：2020-07-03；

[4].     一种调控细胞内NF-κB活性的基因表达载体及其调控方法和应用；申请日：2017-09-11；ZL201710812983.2；发明人：王王进科、汤缓缓；授权日：2019-12-23；

[5].     一种基于单链接头的下一代测序文库的构建方法及其应用；申请日：2017-10-19；ZL201710978737.4；发明人：王进科、武剑      ；授权日：2020-09-23；

[6].     一种基于CRISPR的DNA检测和分型方法及其应用；申请日：2017-11-20；ZL201711157285.X；发明人：王进科、张贝贝；CtPCR2.0；授权日：2020-09-07；

[7].     一种基于Cas9核酸酶的DNA检测分析方法及其应用；申请日：2017-11-17；ZL201711146674.2；发明人：王进科、王巧；CtPCR1.0；2021-04-26；

[8].     一种用于茎环引物-滚环扩增反应的茎环引物以及茎环引物-滚环扩增的应用；申请日：2017-11-20；ZL201711156103.7；发明人：王进科、张贝贝；授权日：2021-04-06；

[9].     一种由NF-κB启动的肿瘤细胞特异效应基因表达载体及其表达产物和应用；申请日：2018-02-27；ZL201810163823.4；发明人：王进科、王丹阳、戴薇；授权日：2020-07-01；

[10].  一种TALE表达载体及其快速构建方法和应用；申请日：2018-07-04；ZL201810723261.4；发明人：王进科、张书衍；授权日：2021-04-28；

[11].  一种CRISPR辅助DNA靶向富集方法及其应用；申请日：2018-09-17；ZL201811082353.5；发明人：王进科、徐新慧；授权日：2021-06-02；

[12].  一种用于核酸快速提取的聚丙烯酰胺微球及其制备方法和应用；申请日：2020-01-14   ；ZL202010035005.3；发明人：王进科、王军；授权日：2021-06-28；

[13].  一种TALEN表达载体及其快速制备方法及靶基因和细胞双标记系统和应用；申请日：2020-01-14；ZL202010035004.9；发明人：王进科、张书衍；授权日：2021-06-16；

[14].  基于cfDNA的测序及数据分析的癌症相关生物标记及其在cfDNA样品分类中的应用；申请日：2020-01-14；ZL202010035114.5；发明人：王进科、刘世财；授权日：2021-08-02；

[15].  一种基于基因干扰载体和铁纳米粒子用于杀灭癌细胞的组合物及其应用；申请日：2020-03-13；ZL202010173472.2；发明人：王进科、高金良、罗涛；授权日：2021-01-13；

[16].  一种基于CRISPR/Cas9的DNA检测方法及其应用；申请日：2020-04-26；ZL202010337705.8；发明人：王进科、徐新慧；授权日：2021-05-24；

[17].  一种基于序列特异性核酸结合蛋白的核酸检测和分型的方法及其应用；申请日：2017-12-08；ZL201711296900.5；发明人：王进科、徐新慧、夏强；授权日：2021-09-01；

[18].  一种CRISPR辅助反式增强子激活基因表达的方法及其应用；申请日：2018-07-26；申请号：ZL201810935298.6；发明人：王进科、徐新慧。授权日：2021-10-11。