导师风采
耿俊华
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个人信息

Personal Information

  • 副研究员
  • 导师类别:硕士生导师
  • 性别: 男
  • 学历:博士研究生
  • 学位:博士

联系方式

Contact Information

  • 所属院系:生命科学与技术学院
  • 所属专业: 生物学
  • 邮箱 : gengjunhua@seu.edu.cn
  • 工作电话 : -

个人简介

Personal Profile

2018-07至今:          东南大学生命科学与技术学院,副研究员

2015-04至2018-06:美国南加州大学,博士后

2014-07至2015-03:南京军区南京总医院,助理研究员

2009-07至2010-08:北京师范大学,科研助理

2010-09至2014-06,北京师范大学,博士

2006-09至2009-06,东南大学,    硕士

2001-09至2005-06,安徽农业大学,学士


  • 研究方向Research Directions
突触结构和功能与疾病的关联
科研项目



研究成果

1. Gan Guangming*, Chen Mei, Yu Qinfeng, GaoXiang, Zhang Chenchen, Sheng Qingyuan*, Xie Wei, Geng Junhua*. Neurexin and neuroligins jointly regulate synapticdegeneration at the Drosophila neuromuscular junction based on TEM studies,Front Cell Neurosci. 2023 Nov 1:17:1257347. doi: 10.3389/fncel.2023.1257347.

2. Sun Yichen, Li Moyi, Geng Junhua, Meng Sibie, Tu Renjun, Zhuang Yan, Sun Mingkuan, RuiMenglong, Ou Mengzhu, Xing Guangling, Travis K Johnson, Xie Wei. Neuroligin 2governs synaptic morphology and function through RACK1-cofilin signaling inDrosophila, Commun Biol. 2023 Oct 18;6(1):1056. doi:10.1038/s42003-023-05428-3.

3. Zhou Xiu, Gan Guangming, Sun Yichen, OuMengzhu, Geng Junhua, Wang Jing,Yang Xi, Huang Shu, Jia Da, Xie Wei, He Haihuai. GTPase-activating proteinTBC1D5 coordinates with retromer to constrain synaptic growth by inhibiting BMPsignaling, J Genet Genomics. 2023 Mar;50(3):163-177. doi:10.1016/j.jgg.2022.11.009.

4. Gan Guangming*, Chen Mei, Zhang Chenchen,Xie Wei, Geng Junhua*. Improvedanalysis method of neuromuscular junction in Drosophila larvae by transmissionelectron microscopy. Anat Sci Int. 2022 Jan;97(1):147-154. doi:10.1007/s12565-021-00635-6.

5  Peng, Yi-Jheng#; Geng, Junhua#; Wu, Ying; Pinales, Cristian ; Langen, Jennifer ;Chang, Yen-Ching ; Buser, Christopher; Chang, Karen T*. Minibrain kinase andcalcineurin coordinate activity-dependent bulk endocytosis throughsynaptojanin, J Cell Biol (2021) 220 (12): e202011028.

6. Gan Guangming*; Geng Junhua; Chen chen; Mou Yang; Xie Wei. Neurexin andNeuroligins maintain the balance of ghost boutons and satellite boutons at theDrosophila neuromuscularjunction, Frontiers in Neuroanatomy, 2020, doi:10.3389/fnana.2020.00019.

7. Lee Joo Yeun; GengJunhua; Lee Juhyun; Wang Andrew R.; Chang Karen T..Activity-InducedSynaptic Structural Modifications by an Activator of IntegrinSignaling at the DrosophilaNeuromuscular Junction. The Journal of neuroscience,2017, 37:3246-3263.

8. GengJunhua#;Xia Lu#; Li Wanjie; Zhao Changqi; Dou Fei. Cycloheximide Treatment Causes aZVAD-Sensitive Protease-Dependent Cleavage of Human Tau in Drosophila Cells.Journal of Alzheimer's disease, 2016:49, 1161-1168.

9. GengJunhua#;Wang Liping#; Lee JooYeun; Chen Chun-Kan; Chang Karen T.. Phosphorylation ofSynaptojaninDifferentially Regulates Endocytosis of Functionally DistinctSynaptic VesiclePools. The Journal of neuroscience, 2016:36, 8882-8894.

10. GengJunhua;Xia Lu; Li Wanjie; DouFei. The C-terminus of tau protein plays an importantrole in its stability andtoxicity. Journal of molecular neuroscience, 2015,55:251-259.

 


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