1. 国家自然科学基金面上项目，82072725、去泛素化酶OTUB2与转录因子GATA2正反馈环路促进结肠癌转移的机制研究、2021.01-2024.12、55万元、在研、主持。

2. 国家自然科学基金面上项目，81872042、MZF1/SETD1A-FoxM1正反馈环路促进结直肠癌侵袭转移的机制研究、2019.01-2022.12、58万元、结题、主持。

3. 江苏省卫健委重点项目，ZD2021039，基于肿瘤类器官-免疫细胞共培养芯片技术构建结直肠癌精准诊疗平台，2022.1-2024.12，20万，在研、主持

4.  国家自然科学基金面上项目，81572457、FoxM1c-miR-149-FoxM1b/c负反馈环路在结肠癌血管生成中的调控作用及分子机制研究、2016.01-2019.12、57万元、结题、主持。

5.  国家自然科学基金面上项目，81272394、叉头框蛋白M1（FoxM1）通过转录激活存活素（survivin）基因表达而参与结肠癌肝转移表型形成的分子机制研究、2013.01-2016.12、65万元、结题、主持。

6.  江苏省自然科学基金面上项目，BK20181238、长链非编码RNA PCAT-1/miR-149/FOXM1信号轴促进结肠癌化疗耐药表型形成的分子机制、2018.07-2021.07、10万、结题、主持。

1.  Chen Yanyan#, Wang Bin#, Huang Mengxi#, Wang Tao#, Hu Chao, Liu Qin, Han Dong, Chen Cheng, Zhang Junliang, Li Zhiping, Liu Chao, Lei Wenbin, Chang Yue, Wu Meijuan, Xiang Dan, Chen Yitian, Wang Rui, Huang Weiqian, Lei Zengjie*, Chu Xiaoyuan*. MAFB Promotes Cancer Stemness and Tumorigenesis in Osteosarcoma through a Sox9-Mediated Positive Feedback Loop. Cancer Research. 2020, 80(12):2472-2483.

2. Chang Y#, Zhao Y#, Wang L#, Wu M#, He C, Huang M, Lei Z, Yang J, Han S, Wang B, Chen Y, Liu C, Yu H, Xue L, Geng J, Chen Y, Dai T, Ren L, Wang Q, Liu X, Chu X*, Chen C*. PHF5A promotes colorectal cancerprogression by alternative splicing of TEAD2. Mol Ther Nucleic Acids. 2021, 26:1215-1227.

3.  Han D#, Huang M#, Wang T#, Li Z, Chen Y, Liu C, Lei Z*, Chu X*. Lysine methylation of transcription factors in cancer. Cell Death Dis. 2019, 10(4): 0-290.

4. Ye Wang#, Meijuan Wu#, Zengjie Lei, Mengxi Huang, Zhiping Li, Liya Wang, Qijun Cao, Dong Han, Yue Chang, Yanyan Chen, Xiaobei Liu, Lijun Xue, Xiaobei Mao, Jian Geng, Yanan Chen, Tingting Dai, Lili Ren, Qian Wang, Hongju Yu, Cheng Chen* and Xiaoyuan Chu*. Dysregulation of miR-6868-5p/FOXM1 circuit contributes to colorectal cancer angiogenesis. Journal of Experimental & Clinical Cancer Research. 2018, 37(1): 292.

5. Ye Wang#, Liya Wang#, Cheng Chen*, Xiaoyuan Chu*. New insights into the regulatory role of microRNA in tumor angiogenesis and clinical implications. Molecular cancer. 2018, 17(1), 22.

6.  Mengxi Huang#, Cheng Chen#, Jian Geng, Dong Han, Tao Wang, Tao Xie, Liya Wang, Ye Wang, Chun hua Wang, Zengjie Lei*, Xiaoyuan Chu*. Targeting KDM1A attenuates Wnt/β-catenin signaling pathway to eliminate sorafenib-resistant stem-like cells in hepatocellular carcinoma[J]. Cancer Letters. 2017, 398: 12-21.