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主要研究方向为光电催化中的质谱原位分析,以及基于微流控技术的外泌体生物传感。近年来,开展了气液界面、电极-电解质界面、外泌体等的分析研究工作,成功实现了高真空下固液气三相界面的原位实时质谱检测,为研究能源与环境、生物动态界面过程提供了重要方法与理论依据。研究成果以第一作者或通讯作者身份发表在Chem. Sci., Environ. Sci. Technol., Anal. Chem.等化学/环境领域重要SCI期刊上。主持包括国家自然科学基金青年基金,上海市自然科学基金,江苏省自然科学面上基金等在内的多个科研项目。入选上海市科委“扬帆计划”,东南大学“至善青年学者”计划,获得2022年度“吾爱吾师”院系最受欢迎教师称号。
• 主持国家自然科学基金青年项目,江苏省自然科学基金面上项目,上海市自然科学基金面上项目,中国博士后科学基金面上项目;
• 入选上海市“青年科技英才”扬帆计划、东南大学“至善青年学者”计划。
代表性论文:
1. L. Song; Y. Ding; Y. Xie; Z. Zhang; X. Hua*; S. Liu,Acceleration of Enzyme-Catalyzed Reactions at Aqueous Interfaces throughEnhanced Reaction Kinetics of Microdroplets. Analytical Chemistry 2025,97 (11), 5992-6000.
2. Z. Zhang; Y. Ding; X. Hua*; L. Song; S. Liu*, AcceleratedSynergistic Photo-Fenton/Photocatalysis Reactions at Aqueous Interfaces. ACS Applied Materials & Interfaces 2025, 17 (8), 12921-12929.
3. Y. Liu; G. Han; J. Gong; X. Hua*; Q. Zhu; S. Zhou; L. Jiang;Q. Li*; S. Liu, Intramolecular Fluorescence Resonance Energy Transfer Strategyfor Accurate Detection of AFP-L3% and Improved Diagnosis of HepatocellularCarcinoma. Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy 2023, 122950.
4. X. Hua; H.-L. Xia; Y.-T. Long*, A tinypore-confined solid-liquid interface for in-situ ToF-SIMS electrochemistry ofnitrobenzoic acid. Electrochimica Acta 2022, 431, 141085.
5. X. Hua; X. Liu; Q. Zhu; Y. Liu; S. Zhou; P. Huang; Q. Li; S. Liu*,Three-Dimensional Microfluidic Chip for Efficient Capture of SecretoryAutophagosomes and Sensitive Detection of Their Surface Proteins. AnalyticalChemistry 2022, 94, 23, 8489–8496.
6. S. ADDIN EN.REFLIST Wu#; X. Hua#(共同一作); B. Ma; H. Fan; R. Miao; M. Ulbricht; C. Hu; J. Qu,Three-Dimensional Analysis of the Natural-Organic-Matter Distribution in theCake Layer to Precisely Reveal Ultrafiltration Fouling Mechanisms. Environmental Science & Technology 2021, 55, 8, 5442–5452.
7. H.-W. Li; Z. Hu; X. Chen; J. Ren; H. Cui; M. Zhang; L. Chen; X. Hua*;J. Song*; Y.-T. Long, Investigation of Lipid Metabolism in Dynamic Progressionof Coronary Artery Atherosclerosis of Humans by Time-of-Flight Secondary IonMass Spectrometry. Analytical Chemistry 2021, 93 (8), 3839-3847.
8. J.-Q. Lou; Y. Cao; Y.-J. Yu; L. Hu; Z.-S. Mao; P. Huang; X. Hua*;F. Chen*, Investigation of heart lipid changes in acute β-AR activation-inducedsudden cardiac death by time-of-flight secondary ion mass spectrometry. Analyst 2020, 145 (17),5889-5896.
9. Y.-Y. Liu; X. Hua*; Z. Zhang; J. Zhang; S. Zhang; P. Hu; Y.-T.Long, pH-Dependent Water Clusters in Photoacid Solution: Real-Time Observationby ToF-SIMS at a Submicropore Confined Liquid-Vacuum Interface. Frontiers in Chemistry 2020, 8 (731).
10. X. Hua; H.-L. Xia; Y.-T. Long*, Revisitinga classical redox process on a gold electrode by operando ToF-SIMS: where doesthe gold go? Chemical Science, 2019, 10, 6215-6219.
11. Y.-Y. Liu; S.-Z. Zhang; Y.-L.Ying; H.-L. Xia; X. Hua*; Y.-T. Long*, Ion-Specific Effects on HydrogenBond Network at a Submicropore Confined Liquid-Vacuum Interface: An in SituLiquid ToF-SIMS Study, The Journal of Physical Chemistry Letters, 2019,10, 17, 4935-4941.
12. J.-G. Wang; X. Hua*; H.-L. Xia; Y.-T. Long*, PoreConfined Liquid-Vacuum Interface for Charge Transfer Study in ElectrochemicalProcess, Analytical Chemistry, 2019, 91, 3195-3198.
13. D. Xu; X. Hua*; L. Xu; W. Wu; Y.-T. Long*; H. Tian, Understanding HowAmbiance Affect the Performance of Hole-Conductor-Free Perovskite Solar Cellsfrom a Chemical Perspective, ACSApplied Energy Materials, 2019,2, 2387–2391.
14. H.-W. Li; X. Hua*; Y.-T. Long, Graphene quantum dots enhanced ToF-SIMS forsingle-cell imaging, Analytical andBioanalytical Chemistry, 2019, 411,4025–4030.
15. X. Hua; H.-W. Li; Y.-T. Long*,Investigation of silver nanoparticle induced lipids changes on single cellsurface by ToF-SIMS, AnalyticalChemistry, 2018, 90, 1072–1076.
16. D. Xu; X. Hua*; S.-C. Liu; H.-W. Qiao; H.-G. Yang; Y.-T. Long*; H. Tian, Insitu and real-time ToF-SIMS analysis of light-induced chemical changes inperovskite CH3NH3PbI3, Chemical Communications, 2018,54, 5434-5437.
17. J. Lu; X. Hua*; Y.-T. Long, Recent advances in real-time and in situanalysis of an electrode–electrolyte interface by mass spectrometry, Analyst, 2017, 142, 691-699.
18. D. Huang; X. Hua*; G.-L. Xiu*; Y.-J. Zheng; X.-Y. Yu*; Y.-T. Long, Secondaryion mass spectrometry: The application in the analysis of atmosphericparticulate matter, Analytica ChimicaActa, 2017, 989, 1-14.
2023.10-至今,东南大学,副教授
2020.11-2023.10,东南大学,讲师
2018.03-2020.09,华东理工大学,特聘副研究员
2016.01-2018.02,华东理工大学,师资博士后
2010.09-2015.12,东南大学,博士,专业:应用化学
2013.04-2015.04,美国Pacific Northwest National Laboratory,联合培养
2006.09-2010.06,东南大学,本科,专业:化学工程与工艺
• 获2022年东南大学教学竞赛三等奖;
• 2022年度“吾爱吾师”院系最受欢迎教师。
2025年度招生专业:化学、化学工程(专业学位)
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