主持的科研项目：

1. 国家自然科学基金项目，青年，32100784，2022-01至2024-12，在研，主持；

2. 江苏省自然科学基金项目，面上，BK20221458，2022-07至2025-07，在研，主持；

3. 南京市留学人员科技创新项目择优资助，1131000109，2021-10至2022-10，在研，主持；

4. 东南大学“至善青年学者”（A层次），2024-01至2026-12，在研，主持；

5. 东南大学高层次人才科研启动项目，2021-01至2022-12，在研，主持。

 参与的科研项目：

1.  科技部，“脑科学与类脑研究”重大项目，2021ZD0204000，2021-12至2026-11，在研，参与；

2. 科技部，重大项目， 2021ZD0204003， 2021-12 至 2026-12，在研，参与；

3.  国家自然科学基金项目，面上，31771592， 2018-01至2021-12，已结题，核心骨干；

4.  国家自然科学基金项目，重点，31430035，201501-201912，已结题，参与；

5.  国家自然科学基金项目，面上，31771510，2020-01至2023-12，在研，参与；

6.  国家自然科学基金项目，青年，31600824，2017-01至2019-12，已结题，参与。

近期代表性论文：(# co-first author; * corresponding author)：

1.  SifanGong #, Shuliu Zhang #, Xu Yan, Wenting Gong, Qingxia Zhou, Xiaojing Yang, KunYang*, Menglong Rui*, Su Wang*. N-myristoylTransferase Maintains Type II Neuroblasts through Notch Signaling in Drosophila.Neuroscience Bulletin. 2026 Jan 3.

2.  QingxiaZhou#, Fuhao Zhang#, Sifan Gong, Shuliu Zhang, Wenting Gong, Menglong Rui*,Su Wang*. Split Ends Inhibits the Dedifferentiation of imINP to Prevent theGeneration of Supernumerary Type II Neuroblasts in Drosophila. Cells.2025 Dec 4;14(23):1926.

3.  BinWang #, Limin Xu#, Menglong Rui*. Progress in Drug-targetedTherapy for Papillary Thyroid Carcinoma. Current Oncology Reports.2025 Nov;27(11):1331-1345.

4.  Ting Zheng, Keyao Long, Su Wang, Menglong Rui*. Glial-derivedTNF/Eiger signaling promotes somatosensory neurite sculpting. Cellular and Molecular Life Sciences. 2025 Jan 21;82(1):47.

5.  Keyao Long#, Erqian Huang#, Yuhao Yuan, Su Wang*, Menglong Rui*. Steering Axon Development: Glial Cell Mechanisms in Drosophila. ACS Chemical Neuroscience. 2025. Sep 7.

6.  Keyao Long, Wanyue Xu, Xun Miao, Su Wang*, Menglong Rui*. Live CellImaging to Monitor Axonal Pruning in Drosophila Motor Neurons. Bio-protocol.2025 Jul 5;15(13): e5367.

7.  Wanting Wang, Menglong Rui*. Advances in understanding the roles of actinscaffolding and membrane trafficking in dendrite development. Journal of Genetics and Genomics. 2024 Nov;51(11):1151-1161.

8.  Menglong Rui*.Recent progress in dendritic pruning of Drosophila C4da sensory neurons.Open Biology. 2024 Jul;14(7):240059.

9.  Ziyang Gao, Erqian Huang, Wanting Wang, Lizhong Xu, Wanyue Xu, Ting Zheng, Menglong Rui*. Patronin regulates presynaptic microtubule organization andneuromuscular junction development in Drosophila. iScience. 2024Jan 18;27(2):108944.

10.  Menglong Rui*, Weiyu Kong, WantingWang, Ting Zheng, Su Wang*, Wei Xie. Droj2 Facilitates Somatosensory NeuriteSculpting via GTP-Binding Protein Arf102F in Drosophila. Int J Mol Sci. 2023 Aug 25;24(17):13213.

11.  Wanyue Xu, Weiyu Kong, Ziyang Gao, Erqian Huang, Wei Xie, Su Wang*, Menglong Rui*. Establishment of a novel axon pruning model of Drosophila motorneuron. Biology Open. 2023 Jan 1;12(1): bio059535.

12.  Menglong Rui#, Kay Siong Ng#,Quan Tang, Shufeng Bu, Fengwei Yu*. Protein phosphatase PP2A regulatesmicrotubule orientation and dendrite pruning in Drosophila. EMBO Reports. 2020 Mar 6;21 (5): e48843.

13.  Menglong Rui#, Shufeng Bu#,Liang Yuh Chew#, Qiwei Wang, Fengwei Yu*. The membrane protein Rawregulates dendrite pruning via the secretory pathway. Development.2020 Oct 9;147(19): dev191155.

14.  YanWang#, Menglong Rui#, Quan Tang,Shufeng Bu, Fengwei Yu*. Patronin governs minus-end-out orientation ofdendritic microtubules to promote dendrite pruning in Drosophila. Elife.2019 Mar 28;8: e39964.

15.  Menglong Rui,Jinjun Qian, Lijuan Liu, Huihui Lv, Junhai Han, Zhengping Jia and Wei Xie*. Theneuronal protein Neurexin directly interacts with the Scribble-Pix complex tostimulate F-actin assembly for synaptic vesicle clustering. Journal of Biological Chemistry. 2017 Sep 1;292(35): 14334-14348.

16.  Quan Tang,Menglong Rui, Shufeng Bu, Yan Wang, Liang Yuh Chew, and FengweiYu*. A microtubule polymerase is required for microtubule orientation anddendrite pruning in Drosophila. The EMBO Journal. 2020 May18;39(10): e103549.

17.  Huanhuan Zhang, Menglong Rui, Zhixin Ma, Sifan Gong, Shuliu Zhang, QingxiaZhou, Congfeng Gan, Wenting Gong, Su Wang*. Golgi-to-ER retrograde transportprevents premature differentiation of Drosophila type II neuroblasts viaNotch-signal-sending daughter cells. iScience. 2023 Nov22;27(1):108545.

18.  Xinwang Zhang, Menglong Rui, Guangmin Gan, Cong Huang, Jukang Yi, HuihuiLv, Wei Xie*. Neuroligin4 regulates synaptic growth via the bone morphogeneticprotein (BMP) signaling pathway at the Drosophila neuromuscularjunction. Journal of Biological Chemistry. 2017 Nov3;292(44):17991-18005.

19.  Renjun Tu, Jinjun Qian, Menglong Rui, Nana Tao, Mingkuan Sun, YanZhuang, HuihuiLv, Junhai Han, Moyi Li and Wei Xie*. Proteolytic cleavage isrequired for functional neuroligin 2 maturation and trafficking in Drosophila.Journal of Molecular Cell Biology. 2017 Jun 1;9(3): 231-242.

20.  ZhixinMa, Wenshu Wang, Xiaojing Yang, Menglong Rui, Su Wang*. Glialferritin maintains neural stem cells via transporting iron required forself-renewal in Drosophila. Elife. 2024Sep 10;13:RP93604.

21.  GuanglinXing#, Moyi Li#, Yichen Sun, Menglong Rui, Yan Zhuang, Huihui Lv,Junhai Han, Zhengping Jia*, Wei Xie*. Neurexin-Neuroligin 1 regulates synapticmorphology and functions via the WAVE regulatory complex in Drosophilaneuromuscular junction. Elife. 2018 Mar 14;7: e30457.

22.  YichenSun,Moyi Li*, Junhua Geng, Sibie Meng, Renjun Tu, Yan Zhuang, Mingkuan Sun, Menglong Rui, Mengzhu Ou, Guangling Xing, Travis K Johnson, Wei Xie*. Neuroligin2governs synaptic morphology and function through RACK1-cofilin signaling in Drosophila.Communications Biology. 2023 Oct 18;6(1):1056.

23.  YuZhao, Junhua Geng, Zhu Meng, Yichen Sun, Mengzhu Ou, Lizhong Xu, Moyi Li, GuangmingGan, Menglong Rui, Junhai Han, Wei Xie. Neurexin facilitatesglycosylation of Dystroglycan to sustain muscle architecture and function in Drosophila.Communications Biology. 2024 Nov 9;7(1):1481.

24.  Xi Xiao, Changyan Chen, Tian-ming Yu, Jiayao Ou, Menglong Rui,Yuanfen Zhai,Yijing He, Lei Xue, and Margaret S. Ho*. Molecular ChaperoneCalnexin Regulatesthe Function of Drosophila Sodium Channel Paralytic. Frontiers in Molecular Neuroscience. 2017 Mar 7;10:57.

25.  Jianzheng He, Alice Mei Xien Tan, SiYun Ng, Menglong Rui, Fengwei Yu*.Cannabinoids modulate food preference and consumption in Drosophilamelanogaster. Scientific Reports. 2021 Feb 25;11(1):4709.