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东南大学,附属中大医院儿科,儿科副主任,主任医师,讲师
教育经历:
1.2011/10-2014/02,德国UlM大学,医学院儿科系,博士,导师:Helmut D Hummler
2.2002/09-2004/07,东南大学,医学院儿科系,硕士,导师:蒋犁
3.1987/09-1992/07,中国医科大学,儿科系,学士
科研与学术工作经历(按时间倒序排序;如为在站博士后研究人员或曾有博士后研究经历,请列出合作导师姓名):
1.2021.04至今,东南大学附属中大医院儿科,主任医师,科副主任
2.2004.08-2021.03,东南大学附属中大医院儿科,副主任医师,讲师
3.2004.01-2004.07, 青海省妇女儿童医院,副主任医师
4.1998.12-2003.12,青海省儿童医院,主治医师
5.1992.08-1998.11,青海省儿童医院,住院医师
1.省妇幼健康科研项目,重点支持项目,202114,“促红细胞生成素联合亚低温治疗新生儿缺氧缺血性脑损伤的疗效及机制研究”,2022.01-2024.12。项目主持人。
2.国家自然基金,81771628“促红细胞生成素经EPOR/PI3K/Akt信号通路调控早产儿脑白质损伤血管修复的机制研究”2018.01-2021.12.第三主持人。
3.国家自然基金,81601355“基于EPOR-ERK信号通路探讨EPO干预早产儿脑白质损伤中血管新生的机制”2017.01-2019.12.第二主持人。
4.江苏省自然科学基金,BK20151420,生命早期肠道菌群定植对发育期哮喘气道炎症的影响,2015/07-2018/06,10万,参与。
5.德国巴登符特州际科学基金,The effect of different ventilation support on the asphyxiated newborn piglets,2011/07-2014/06,10万欧元,参与。
5.南京市医学科技发展基金,NK2006302,新生脑缺氧缺血后海马神经干细胞再生研究,2007/01-2010/12,9万,参与。
6.注册并负责了“EPO联合亚低温治疗新生儿缺氧缺血性脑损伤的疗效及机制研究”(注册号:ChiCTR-ONC-16008744)。
1、期刊论文
(1)Huang L*, Mendler MR, Waitz M, Schmid M, Hassan MA, Hummler HD. Effects of Synchronization during Noninvasive Intermittent Mandatory Ventilation in Preterm Infants with Respiratory Distress Syndrome Immediately after Extubation. Neonatology, 2015,108(2):108-114.
(2)黄莉,朱欢,乔立兴,尹莉萍,郑意楠,唐洪丽,蒋犁.固尔苏联合高频振荡通气治疗新生儿中重度肺透明膜病的疗效.江苏医药,2013,39(4):471-473.
(3)黄莉,蒋犁,缪红军. 神经生长因子对新生大鼠脑神经元细胞缺氧缺血损伤的保护作用.中国临床康复,2005, 9(45):82-84.
(4)Hassan MA, Mendler M, Maurer M, Waitz M, Huang L, Hummler HD*. Reliability of Pulse Oximetry during Cardiopulmonary Resuscitation in a Piglet Model of Neonatal Cardiac Arrest. Neonatology, 2015,107(2):113-119.
(5) Mendler MR, Maurer M, Hassan MA, Huang L, Waitz M, Mayer B, Hummler HD.Different Techniques of Respiratory Support Do Not Significantly Affect Gas Exchange during Cardiopulmonary Resuscitation in a Newborn Piglet Model.Neonatology. 2015;108(1):73-80
(6) Mendler MR, Weber C, Hassan MA, Huang L, Waitz M, Mayer B, Hummler HD. Effect of Different Respiratory Modes on Return of Spontaneous Circulation in a Newborn Piglet Model of Hypoxic Cardiac Arrest. Neonatology. 2016;109(1):22-30
(7) Mendler MR, Weber C, Hassan MA, Huang L, Mayer B, Hummler HD. Tidal Volume Delivery and Endotracheal Tube Leak during Cardiopulmonary Resuscitation in Intubated Newborn Piglets with Hypoxic Cardiac Arrest Exposed to Different Modes of Ventilatory Support. Neonatology. 2016 Sep 20;111(2):100-106.
(8) Hassan MA, Weber C, Waitz M, Huang L, Hummler HD, Mendler MR. Reliability of Pulse Oximetry during Progressive Hypoxia, Cardiopulmonary Resuscitation, and Recovery in a Piglet Model of Neonatal Hypoxic Cardiac Arrest. Neonatology 2017;112:40–46
(9) Zhu L, Huang L, Wen Q, Wang T, Qiao L, Jiang L. Recombinant human erythropoietin offers neuroprotection through inducing endogenous erythropoietin receptor and neuroglobin in a neonatal rat model of periventricular white matter damage. Neurosci Lett. 2017 May 22;650:12-17.
(10) Huang L*, Qiao LX, Zhu H, Jiang L and Yin L. Genomics of neonatal sepsis: has-miR-150 targeting BCL11B functions in disease progression. Italian Journal of Pediatrics (2018) 44:145-151
(11) Yin LP, Zhu H, Zhu RY, Huang L*. A novel SCNN1G mutation in a PHA I infant patient correlates with nephropathy, Biochemical and Biophysical Research Communications. 2019, 519(2): 415-421.
2、会议论文
(1)Huang L, Mendler MR, Waitz M, Schmid M, Hummler HD*. Effects of synchronization during noninvasive intermittent mandatory ventilation in very low birth weight infants (VLBWI) recovering from RDS immediately after extubation. Pediatric Academic Societies, American,2013.5.17-5.20.
(2)Huang L, Mendler MR, Waitz M, Schmid M, Hassan MA, Hummler HD*. The Effects of Synchronization Supported by Nasal Ventilation Via Naso-Pharyngeal Tube or Bi-Nasal Short Prong on VLBW Infants With RDS Immediately after Extubation. Pediatric Academic Societies and Asia Society for Pediatric Research, Vancouver, BC, Canada,2014.5.3-5.6.
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