【王苏导师】招生“生命科学与技术学院”研究生介绍
王苏
教授
硕，博士生导师
男
生命科学与技术学院
生物学
神经干细胞,神经发育
wangsu@seu.edu.cn
2010于北京大学获得学士学位，2015于美国堪萨斯大学医学中心获得博士学位，并在美国Stowers医学研究所担任博士生研究员。2017年加入东南大学生命科学与技术学院担任教授，兼“发育与疾病”相关基因教育部重点实验室副主任，东南大学生命科学与技术学院教师党支部书记。分别入选中组部“青年千人”，江苏省特聘教授，江苏省双创人才，江苏省“六大人才高峰”高层次人才。任江苏省发育生物学学会理事。
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科研项目
1. 国家自然科学基金委员会，面上项目，31970675，Mnt对果蝇神经干细胞行为和命运决定调控机制的研究，2020-2023，主持，在研。
2. 国家自然科学基金委员会，面上项目，31771510，微环境中缝隙连接对果蝇神经干细胞自我更新与分化的调控机制，2018-2019，主持，结题。
3. 东南大学-南京医科大学合作研究项目，应用果蝇和小鼠模型研究sACE 对精原干细胞的调控功能及机制，2017-2020，主持，结题。
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研究成果
1. Mengzhu Ou#, Su Wang#, Mingkuan Sun, Jinsong An, Huihui Lv, Xiankun Zeng, Steven X. Hou*, Wei Xie*.: The PDZ-GEF Gef26 regulates synapse development and function via FasII and Rap1 at the Drosophila neuromuscular junction. Experimental Cell Research. 2019 Jan 15; 374(2):342-352. doi: 10.1016/j.yexcr.2018.12.008.
2. Tingting Gao#, Xin Zhao#, Chenchen Liu#, Binbin Shao#, Xi Zhang, Kai Li, Jinyang Cai, Su Wang*, Xiaoyan Huang*.: Somatic Angiotensin I-Converting Enzyme Regulates Self-Renewal of Mouse Spermatogonial Stem Cells Through the Mitogen-Activated Protein Kinase Signaling Pathway. Stem Cells and Development. 2018 Aug 1;27(15):1021-1032. doi: 10.1089/scd.2017.0287.
3. Xing Ma#, Xiujuan Zhu, Yingying Han, Benjamin Story, Trieu Do, Xiaoqing Song, Su Wang, Ying Zhang, Marco Blanchette, Madelaine Gogol, Kate Hall, Allison Peak, Perera Anoja, Ting Xie*.: Aubergine Controls Germline Stem Cell Self-Renewal and Progeny Differentiation via Distinct Mechanisms. Developmental Cell. 2017 Apr 24; 41(2):157-169. e5. doi: 10.1016/j.devcel.2017.03.023.
4. Tinglin Lu#, Su Wang#, Yuan Gao, Ying Mao, Zhihao Yang, Luping Liu, Xiaoqing Song, Jianquan Ni, Ting Xie*.: COP9-Hedgehog axis regulates the function of the germline stem cell progeny differentiation niche in the Drosophila ovary. Development. 2015 Dec 15;142(24):4242-52.
5. Su Wang#, Yuan Gao, Xiaoqing Song, Xing Ma, Xiujuan Zhu, Ying Mao, Zhihao Yang, Jianquan Ni, Hua Li, Kathryn E Malanowski, Perera Anoja, Jungeun Park, Jeff Haug, Ting Xie*.: Wnt Signaling-Mediated Redox Regulation Maintains the Germline Stem Cell Differentiation Niche. eLife. 2015 Oct 9; 4. doi: 10.7554/eLife.08174
6. Lei Pan#, Su Wang#, Tinglin Lu#, Changjiang Weng, Xiaoqing Song, Joseph K. Park, Jin Sun, Zhi-HaoYang, JunjingYu, Hong Tang, Dennis M. McKearin, Daniel A. Chamovitz, Jianquan Ni，Ting Xie*.: Protein competition switches the function of COP9 from self-renewal to differentiation. Nature. 2014 Oct 9; 514(7521):233-6.
7. Xing Ma#, Su Wang, Trieu Do, Xiaoqing Song, Mayu Inaba, Yoshiya Nishimoto, Lu-ping Liu,Yuan Gao, Ying Mao, Hui Li, William McDowell, Jungeun Park, Kate Malanowski, Allison Peak, Anoja Perera, Hua Li, Karin Gaudenz, Jeff Haug, Yukiko Yamashita, Haifan Lin, Jian-quan Ni, Ting Xie*.: Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary. PLoS One. 2014 Mar 21; 9(3):e90267.
8. Xiaoxi Wang#, Lei Pan#, Su Wang#, Jian Zhou, William McDowell, Jungeun Park, Jeff Haug, Karen Staehling, Hong Tang, Ting Xie*.: Histone H3K9 trimethylase Eggless controls germline stem cell maintenance and differentiation. PLoS Genet. 2011 Dec 22; 7(12):e1002426.
9. Daniel Kirilly#, Su Wang#, Ting Xie*.: Self-maintained escort cells form a germline stem cell differentiation niche. Development. 2011 Dec; 138(23):5087-97.
10. Shuyi Chen#, Su Wang, Ting Xie*.: Restricting self-renewal signals within the stem cell niche: multiple levels of control. Curr Opin Genet Dev. 2011 Dec; 21(6):684-9.
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