
陈强,博士,副研究员,硕士研究生导师。2005年获西安建筑科技大学土木工程专业学士学位,2008年硕士毕业于东南大学结构工程专业,同年受国家留学基金委资助赴意大利都灵理工大学攻读博士学位,于2012年获结构工程博士学位并加入东南大学生物科学与医学工程学院。2014年破格晋升为副研究员,并以访问教授身份访问意大利特伦托大学和德国基尔大学。研究领域为骨生物力学及心血管生物力学,近10年来,主要聚焦于骨/骨组织工程及心血管领域中相关生物力学问题的研究,包括:设计骨/心血管支架结构并评估其力学性能;发展支架降解、不可降解支架内骨长入、聚合物骨支架降解-骨生成耦合的数学模型等。主持和参与国家自然科学基金6项(主持2项),其他项目5项(主持3项)。发表论文60余篇(SCI期刊论文58篇,一作及通讯40余篇),国内外学术会议邀请报告8次,被引1000余次。
世界华人生物医学工程协会(WACBE)终身会员, 中国生物医学工程学会生物力学分会终身会员, 中国生物材料学会材料生物力学分会会员, 江苏省力学会生物力学专委会副主任委员等。任Medicine in Novel Technology and Devices杂志Section Editor, BMC Musculoskeletal Disorders杂志编委, Frontiers in Bioengineering and Biotechnology杂志Guest Editor, Digital Medicine杂志青年编委等, 30余种SCI期刊审稿人。
东南大学生物力学团队由李志勇教授于2010年回国后组建,有教授2名,副教授2名,讲师1名。团队主要研究方向包括血管生物力学和骨生物力学。主要针对心脑血管疾病诊治及骨组织修复的重大临床需求,围绕生物力学与疾病发生发展之间相互关系的关键科学问题,以多学科交叉融合的学术思想,采用理论推导、数值计算和生物实验相结合的方法和多维度的技术手段,开展多层面的模型、在体和离体实验,探索心脑血管疾病和骨组织再生的基本生物力学机理和生物物理规律,并发展疾病的防治新方法。近五年来,该团队承担国家和省部级科研项目10余项,在易损斑块早期判定、动脉瘤破裂风险评估、血流动力学、血管新生、骨组织再生和支架降解、多尺度力学建模和生物材料力学测试等领域开展了一系列的研究。发现了斑块内应力同其易损性的关联规律;建立了斑块病变和血管新生的理论模型和数值计算方法;发展了基于医学图像的血流-血管相互作用的流固耦合模型和计算方法;建立了骨组织再生和支架降解的耦合力学生物学模型和计算方法。相关成果持续发表在生物力学领域的核心刊物上,积极推动着生物力学学科的发展。
主持和参与国家自然科学基金6项(主持2项),其他项目5项(主持3项),部分主持项目如:
[1]. 国家自然科学基金委面上项目,32171307,2022/01-2025/12
[2]. 国家自然科学基金委青年基金,31300780,2014/01-2016/12
[3]. 东南大学优秀青年教师资助计划,2015年度, 2016/01-2018/12
[4]. 江苏省高等教育机构优势学科发展项目, 2015年度, 2013/06-2014/06
发表论文60余篇(SCI期刊论文58篇,一作及通讯40余篇),国内外学术会议邀请报告8次。代表性论著(*共同一作,#共同通讯)如:
[1]. Wang L*, Chen Q*, Yarlagadda PKDV, Zhu FP, Li QW, Li ZY. Single-parameter mechanical design of a 3D-printed octet truss topological scaffold to match natural cancellous bones. Materials & Design, 2021, 209:109986.
[2]. Wei L, Wang J, Chen Q#, Li ZY#. Impact of stent malapposition on intracoronary flow dynamics: an optical coherence tomography-based patient-specific study. Medical Engineering & Physics, 2021, 94: 26-32.
[3]. Wang L, Shi Q, Cai Y#, Chen Q#, Guo XY, Li ZY#. Mechanical–chemical coupled modeling of bone regeneration within a biodegradable polymer scaffold loaded with VEGF. Biomechanics and Modeling in Mechanobiology, 2020, 19: 2285-2306.
[4]. Shi Q, Shui H, Chen Q#, Li ZY#. How does mechanical stimulus affect the coupling process of the scaffold degradation and bone formation: An in silico approach. Computers in Biology and Medicine, 2020, 117:103588.
[5]. Wei L, Leo HL, Chen Q#, Li ZY#. Structural and hemodynamic analyses of different stent structures in curved and stenotic coronary artery. Frontiers in Bioengineering and Biotechnology, 2019, 7: 366.
[6]. Wang T#, Qu G, Wang C, Cheng Y, Shang J, Zheng J, Feng ZQ,Chen Q#, He NY. Importance of polyacrylamide hydrogel diverse chains and cross-linking density for cell proliferation, aging, and death. Langmuir, 2019,35(43): 13999-14006.
[7]. Shui H, Shi Q, Pugno NM, Chen Q#, Li ZY#. Effect of mechanical stimulation on the degradation of poly (lactic acid) scaffolds with different designed structures. Journal of the Mechanical Behavior of Biomedical Materials, 2019, 96: 324-333.
[8]. Wei L, Chen Q#, Li ZY#. Influences of plaque eccentricity and composition on the stent–plaque–artery interaction during stent implantation. Biomechanics and Modeling in Mechanobiology, 2019, 18(1): 45-56.
[9]. Liu L, Shi Q, Chen Q#, Li ZY#. Mathematical modeling of bone in-growth into undegradable porous periodic scaffolds under mechanical stimulus. Journal of Tissue Engineering, 2019, 10: 2041731419827167.
[10]. Shi Q, Chen Q#, Pugno, NM, Li ZY#. Effect of rehabilitation exercise durations on the dynamic bone repair process by coupling polymer scaffold degradation and bone formation. Biomechanics and Modeling in Mechanobiology, 2018, 17(3): 763-775.
[11]. Chen Q, Wang Y, Li ZY. Re-examination of the mechanical anisotropy of porcine thoracic aorta by uniaxial tensile tests. Biomedical Engineering Online, 2016, 15(2): 493-506.
[12]. Chen Q, Shi Q, Signetti S, Sun FF, Li ZY, Zhu FP, He SY, Pugno NM. Plastic collapse of cylindrical shell-plate periodic honeycombs under uniaxial compression: experimental and numerical analyses. International Journal of Mechanical Sciences, 2016, 111: 125-133.
[13]. Chen Q, Baino F, Spriano S, Pugno NM, Vitale-Brovarone C. Modelling of the strength–porosity relationship in glass-ceramic foam scaffolds for bone repair. Journal of the European Ceramic Society, 2014, 34(11):2663-2673.
[14]. Chen Q, Shi Q, Gorb SN, Li ZY. A multiscale study on the structural and mechanical properties of the luffa sponge from Luffa cylindrica plant. Journal of Biomechanics, 2014, 47(6): 1332-1339.
[15]. Chen Q, Pugno N, Zhao K, Li ZY. Mechanical properties of ahollow-cylindrical-joint honeycomb. Composite Structures, 2014, 109: 68-74.
[16]. Chen Q, Gorb SN, Gorb E, Pugno NM. Mechanics of plant fruit hooks. Journal of The Royal Society Interface, 2013, 10(81): 20120913.
[17]. Chen Q, Baino F, Pugno NM, Vitale-Brovarone C. Bonding strength of glass-ceramic trabecular-like coatings to ceramic substrates for prosthetic applications. Materials Science and Engineering: C, 2013, 33(3):1530-1538.
[18]. Chen Q, Pugno NM. Bio-mimetic mechanisms of natural hierarchical materials: a review. Journal of the Mechanical Behavior of Biomedical Materials, 2013, 19: 3-33.
[19]. Chen Q, Pugno NM. In-plane elastic buckling of hierarchical honeycomb materials. European Journal of Mechanics-A/Solids,2012, 34: 120-129.
[20]. Chen Q, Pugno NM. Modeling the elastic anisotropy of woven hierarchical tissues. Composites Part B: Engineering, 2011, 42(7):2030-2037.
世界华人生物医学工程协会(WACBE)终身会员
中国生物医学工程学会生物力学分会终身会员
中国生物材料学会材料生物力学分会会员
江苏省力学会生物力学专委会副主任委员
Medicine in Novel Technology and Devices,Section Editor
Frontiers in Bioengineering and Biotechnology: Biomaterials,Guest Editor
BMC Musculoskeletal Disorders,Editorial Board Member
Frontiers in Materials: Biomaterials, Review Editor
Frontiers in Bioengineering and Biotechnology: Biomechanics,Review Editor
Frontiers in Manufacturing Technology: Additive Processes,Review Editor
Digital Medicine,Youth Editorial Member
《医用生物力学》特约审稿人
30余种SCI期刊审稿人。