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中国生物医学工程学会类器官与器官芯片分会委员,江苏省解剖学会理事。已在Journalof Neuroscience和Molecular Cell, Molecular Neurodegeneration等杂志上发表第一作者文章6篇,合作者文章3篇。完成国家自然科学基金青年基金项目,中国博士后科学基金面上项目和江苏省自然科学基金青年基金项目各1项,参与国家自然科学基金重点项目1项。先后入选(获)南京大学“优秀博士生创新能力提升计划”(2015)、东南大学“至善青年学者”(2021)。
中国博士后科学基金面上项目《研究PQBP1在皮层发育中的作用及机制》2017M611650,2017.07-2018.12,5万元,项目负责人,已结题;
江苏省科技计划项目-青年项目《PQBP1在大脑皮层中调控自我增殖和分化的作用机制研究》BK20170703,2017.07-2020.06,20万元,项目负责人,已结题;
国家自然科学基金-青年项目《PQBP1调控神经元轴树突生长发育的机制研究》31800862,2019.01-2021.12,25万元,项目负责人,已结题;
国家自然科学基金-重点项目《PQBP1基因突变导致智力障碍的机制究》31771171,2018.01-2022.12,290万,主要参与人。
1. ChengS,Shen Y, Zhang Z*, Han J*. Protocol for interfering peptide injection into adultmouse hippocampus and spatial memory testing. STARProtocols,2021.
2. Shen Y#, Zhang Z#, ChengS#, Liu A, Zou J, Xia S, Liu X, LiuW, Jia Z, Xie W,Han J*.PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTDthrough suppressing eEF2 phosphorylation. Molecularcell.2021,81,1425–1438, IF = 15.584, Q1
3.Cheng S#, Liu T#, Hu Y#, XiaY, Hou J,Huang C, Zou X, Liang J, Shi YS, Zheng Y, Lu J*, ChenG*.Conditional Inactivation of Pen-2 in the Developing Neocortex Leads to RapidSwitch of Apical Progenitors to Basal Progenitors. Journal ofNeuroscience,2019, 39(12):2195–2207. IF = 6.335, Q1,
4. Wang L#, ChengS#, Yin Z, Xu C, Lu S, Hou J,Yu T, Zhu X, Zou X, Peng Y, Xu Y, Yang ZZ, Chen G*.Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation inthe brain. Molecular Neurodegeneration,2015, 10: 1~7. IF = 9.599, Q1
5. ChengS#, Hou J, Zhang C, Xu C, Wang L, Zou X,Yu, H, Shi Y, Yin Z, Chen G*. Minocycline reduces neuroinflammation butdoes not ameliorate neuron loss in a mouse model of neurodegeneration. Scientific Reports,2015, 5: 1-14. IF = 3.998, Q3
6. ChengS#, Zhang C, Xu C, Wang L, Zou X,Chen G*.Age-dependent neuron loss is associated with impaired adult neurogenesis inforebrain neuron-specific Dicer conditional knockout mice. TheInternational Journal of Biochemistry & Cell Biology,2014, 57:186-96. IF = 3.673, Q3
7. Gu Q,Wu J, Tian Y, Cheng S,Zhang Z, Han J*. Gαq splice variants mediate phototransduction,rhodopsin synthesis, and retinal integrity in Drosophila. J. Biol. Chem.2020, 295(17) 5554–5563. IF = 4.238, Q2
8. Hou J, ChengS,Chen L, Wang Q, Shi Y, Xu Y, Yin Z, Chen G*.Astroglialactivation and tau hyperphosphorylationprecede to neuron loss in a neuro- degenerative mouse model, CNS Neurosci Ther. , 2016.05.22, 244~247.IF =4.074, Q2
9. Liu TT, Ye XL, Zhang JP, Yu TT, ChengSS, ZouXC, Xu Y, Chen GQ, Yin ZY*. Increasedadult neurogenesis associated with reactive astrocytosisoccurs prior to neuron loss in a mouse model of neurodegenerative disease. CNS Neurosci Ther.2017 Nov;23(11):885-893. IF = 4.074, Q2
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