博士生：赵静（已毕业）、杨惠泉、李冬冬、李帆、曹玉玉

硕士生：金海振（已毕业）、赵静（硕博连读）、李冬冬（硕博连读）、陈文彬（已毕业）、曹玉玉（硕博连读）、马靖

长期从事纳米医学研究，侧重研究功能性纳米材料（如纳米银、纳米金包银等）的靶向设计与构建、辐射增敏或化疗增敏对肿瘤转归的影响，探讨免疫反应及自噬在其中的作用及其调控，寻找纳米材料增敏关键通路信号分子。这些研究结果有望向临床转化，用于肿瘤新型增敏剂的研发。相关研究成果已在Nanoscale、Int J Nanomedicine、Nanotechnology等国际期刊上发表，发表SCI收录论文二十余篇。研究获得一项国家重点基础研究发展计划项目子课题和两项国家自然科学基金面上项目的资助，均为项目主持人。主要参加国家重大科学仪器设备开发专项及国家自然科学基金等项目多项。

1. 国家自然科学基金面上项目：双靶点靶向载药银纳米复合物光热-化疗联合治疗乳腺癌的实验研究(项目号81771980)，50万，2018.01-2021.12. 负责人

2. 国家自然科学基金面上项目：新型靶向探针GMT8-Ag@Au的构建及其在脑胶质瘤CT成像和辐射增敏一体化中的实验研究(项目号81571805)，67.2万，2016.01-2019.12. 负责人

3. 国家重点基础研究发展计划（973计划）子课题：纳米材料调控自噬在肿瘤诊疗中的应用 (项目号2013CB933904)，292万，2013.1-2017.8. 负责人

4. 国家重大科学仪器设备开发专项计划项目“高通量细胞分选多模式检测分析仪器及应用研究”子课题：单细胞与细胞团拉曼光谱检测系统(项目号2011YQ03013403)，600万，2011.10-2016.9. 骨干成员

5. 国家自然科学基金：医用胶体银的可控连续合成及其在脑胶质瘤放疗中的特殊细胞效应与敏化 (项目号51201034)，25万，2013.01-2015.12. 主要参加

1.       Jing Zhao, Dongdong Li, Jun Ma, Huiquan Yang,Wenbin Chen, Yuyu Cao, Peidang Liu*.Increasing the accumulation of aptamer AS1411 and verapamil conjugated silvernanoparticles in tumor cells to enhance the radiosensitivity of glioma. Nanotechnology,2021, 32(14): 145102

2.       Huiquan Yang, Jing Zhao, Dongdong Li, YuyuCao, Fan Li, Jing Ma, Peidang Liu*. Applicationof silver nanotriangles as a novel contrast agent in tumor computed tomographyimaging. Nanotechnology, 2021, 32(49): 495705

3.       Huiquan Yang, Wenbin Chen, Jun Ma, Jing Zhao,Dongdong Li, Yuyu Cao, Peidang Liu*.Silver nanotriangles and chemotherapeutics synergistically induce apoptosis in gliomacells via a ROS-dependent mitochondrial pathway. Int J Nanomedicine, 2020, 15:7791-7803

4.       PeidangLiu, Huimin Shao, Yan Kong, Dayong Wang*. Effect of graphene oxide exposureon intestinal Wnt signaling in nematode Caenorhabditis elegans. J EnvironSCI-CHINA, 2020, 88: 200-208

5.       Jing Zhao, Peidang Liu*, Jun Ma, Dongdong Li, Huiquan Yang, Wenbin Chen,Yaowen Jiang. Enhancement of radiosensitization by silver nanoparticlesfunctionalized with polyethylene glycol and aptamer As1411 for gliomairradiation therapy. Int J Nanomed, 2019, 14: 9483-9496

6.       PeidangLiu*, Huiquan Yang, Wenbin Chen, Jing Zhao, Dongdong Li. Silver nanotrianglesand chemotherapy drugs synergistically induce apoptosis in breast cancer cellsvia production of reactive oxygen species. J Nanopart Res, 2019, 21(11):250

7.       PeidangLiu, Dan Li, Wenjie Li, Dayong Wang. Mitochondrialunfolded protein response to microgravity stress in nematode Caenorhabditiselegans. Sci Rep, 2019, 9(1): 16474

8.       PeidangLiu, Huimin Shao, Xuecheng Ding, Ruilong Yang, Qi Rui, Dayong Wang. Dysregulationof neuronal Gαo signaling by graphene oxide in nematode caenorhabditis elegans.Sci Rep, 2019, 9(1): 6026

9.       Feng Chen, Xiaohong Zhang, Xiaodan Hu, Peidang Liu* and Haiqian Zhang*.Mechanism of increased in vitro radio sensitivity by ceria nanoparticle-neogambogicacid combination. Nanosci Nanotech Lett. 2018, 10(2): 259-266

10.    Feng Chen,Xiaohong Zhang, Xiaodan Hu, Peidang Liu*and Haiqian Zhang*. The effects of combined selenium nanoparticles andradiation therapy on breast cancer cells in vitro. Artif Cells NanomedBiotechnol. 2018, 46(5): 937-948

11.    NingningMa, Peidang Liu, Nongyue He, NingGu, Fu-Gen Wu*, and Zhan Chen*. Action of Gold Nanospikes-BasedNanoradiosensitizers: Cellular Internalization, Radiotherapy, andAutophagy. ACS Appl Mater Interfaces, 2017, 9(37): 31526-31542

12.    Peidang Liu*, Haizhen Jin, ZhiruiGuo, Jun Ma, Jing Zhao, Dongdong Li, Hao Wu and Ning Gu*. Silver nanoparticlesoutperform gold nanoparticles in radiosensitizing U251 cells in vitro and in anintracranial mouse model of glioma. Int J Nanomed. 2016; 11: 5003-5014

13.    Feng Chen,Xiaohong Zhang, Xiaodan Hu, Wei Zhang, Rong Zeng, Peidang Liu* and Haiqian Zhang*. Synthesis and characteristics ofnanorods of gadolinium hydroxide and gadolinium oxide. J Alloy Compd. 2016,664: 311-316

14.    Zhichao Lou, Zhiwei Zhou, Wei Zhang, Xiaohong Zhang, Xiaodan Hu, Peidang Liu*, Haiqian Zhang*. Magnetized bentonite by Fe3O4 nanoparticles treated asadsorbent formethylene blue removal from aqueous solution: Synthesis, characterization,mechanism, kinetics and regeneration. J Taiwan Inst Chem E. 2015, 49:199-205

15.    Feng Chen,Xiaohong Zhang, Xiaodan Hu, Wei Zhang, Zhichao Lou, Lihua Xie, Peidang Liu* and Haiqian Zhang*. Enhancementof radiotherapy by ceria nanoparticles modified with neogambogic acid in breastcancer cells. Int J Nanomed. 2015, 10:4957-4969

16.    Peidang Liu#, ZhihaiHuang#, Zhongwen Chen,Ruizhi Xu, Hao Wu, Fengchao Zang, Cailian Wang, and Ning Gu. Silvernanoparticles: a novel radiation sensitizer for glioma? Nanoscale, 2013, 5 (23):11829-11836

17.    Peidang Liu, Zhihai Huang, NingGu. Exposure to silver nanoparticles does not affect cognitive outcome orhippocampal neurogenesis in adult mice. Ecotox Environ Safe, 2013, 87: 124-130

18.    Peidang Liu#, Kewen He#, Yinxia Li, Qiuli Wu, PengYang, and Dayong Wang. Exposure to mercury causes formation ofmale-specific structural deficits by inducing oxidative damage in nematodes. EcotoxEnviron Safe, 2012, 79: 90-100

19.    Qiuli Wu#, Peidang Liu#, Yinxia Li#, Min Du, Xiaojuan Xing, and Dayong Wang. Inhibition ofROS elevation and damage to mitochondrial function prevents lead-inducedneurotoxic effects on structures and functions of AFD neurons in Caenorhabditiselegans. J Environ SCI-CHINA, 2012, 24 (4): 733-742

20.    Peidang Liu, Ling Chen, XiuyingBai, Andrew Karaplis, Dengshun Miao, and Ning Gu. Impairment of spatiallearning and memory in transgenic mice overexpressing human fibroblast growthfactor-23. Brain Res, 2011, 1412: 9-17