导师风采
沈艳飞
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个人信息

Personal Information

  • 教授
  • 导师类别:硕,博士生导师
  • 性别: 女
  • 学历:博士研究生
  • 学位:博士

联系方式

Contact Information

  • 所属院系:医学院
  • 所属专业: 临床检验诊断学  、 化学
  • 邮箱 : 101011770@seu.edu.cn
  • 工作电话 : -

个人简介

Personal Profile

围绕纳米生物技术与临床诊断,通过富勒烯和氧化钨量子点等半导体功能材料的分子设计与生物传感界面构筑等途径,构建光电/电化学发光诊断新体系。在J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Sci., Anal. Chem.等期刊发表SCI论文100余篇,所发表论文被SCI期刊论文引用4000余次。主持国家自然科学基金面上项目等省部级基金6项,入选江苏省“六大人才高峰”第十一批高层次人才,获江苏省优秀青年基金资助。
  • 研究方向Research Directions
纳米生物技术与临床检验,生物传感
团队展示

IMG_20211127_140845



科研项目
(1)    TMOs量子点增强的电化学发光研究及在分泌型自噬小体检测中的应用
国家自然科学面上项目/ 22074015……………1/1/2021-12/31/2024
资助金额:63万, 主持, 在研
(2)    富勒烯功能材料的界面组装及其在乳腺癌早期诊断中的应用
国家自然科学面上项目/21675022…………1/1/2017-12/31/2020 
资助金额:65万, 主持, 结题
(3)    碳纳米功能材料的制备及其在食品安全检测中的应用
江苏省优秀青年基金/BK20170084…………7/1/2017-6/30/2020
资助金额:50万, 主持, 结题 
(4)    碳基光电转换复合材料的制备及性能研究 
江苏省科技厅青年基金/BK20130788…………7/1/2014-6/30/2017
资助金额:20万, 主持, 结题
(5)    富勒烯-石墨烯功能材料的合成、组装与光电转换基础研究
国家自然科学青年基金/21305065……………1/1/2014-12/31/2016 
资助金额:25万, 主持, 结题
(6)    用于肺癌早期检测的碳纳米生物器件的研发
江苏省“六大人才高峰”项目/2014-XCL-009, 1/1/2015-12/31/2017
资助金额:10万, 主持, 结题
研究成果

https://yshen.group/publications.html

2021

  1. Zhenqiang Ning, Erli Yang, Yongjun Zheng, Mengyuan Chen, Guoqiu Wu, Yuanjian Zhang and Yanfei Shen*, A Dual Functional Self-Enhanced Electrochemiluminescent Nanohybrid for Label-Free MicroRNA Detection. Anal. Chem., 2021, 93, 8971-8977.(IF: 6.986)
  2. Zhenqiang Ning, Mengyuan Chen, Guoqiu Wu, Yuanjian Zhang and Yanfei Shen*, Recent advances of functional nucleic acids-based electrochemiluminescent sensing. Biosens. Bioelectron. 2021, 191, 113462.(IF: 10.618)

2020

  1. Deng Pan,# Zhengzou Fang,# Erli Yang,# Zhenqiang Ning, Qing Zhou, Kaiyang Chen, Yongjun Zheng, Yuanjian Zhang, and , Yanfei Shen*, Facile Preparation of WO3-x Dots with Remarkably Low Toxicity and Uncompromised Activity as Coreactants for Clinic Diagnosis by Electrochemiluminescence. Angew. Chem. Int. Ed., 2020, 59, 16747–16754.[abs] (IF: 12.959) see also in [ChemRxiv, Highlighted by X-MOL---无配体水溶性WO3-x纳米点的绿色制备和绿色电化学发光应用]
  2. Yongjun Zheng, Zhenqiang Ning, Deng Pan, Dan Han, Yuan Xu, Songqin Liu, Yuanjian Zhang, Yanfei Shen*, Electrochemiluminescent detection of hNQO1 and associated drug screening enabled by futile redox cycle reaction. Sens. actuators. B Chem. 2020, 321,1285574
  3. Mengyuan Chen, Zhenqiang Ning, Kaiyang Chen, Yuanjian Zhang*, Yanfei Shen*, Recent Advances of Electrochemiluminescent System in Bioassay, Journal of Analysis and Testing, 2020, 4, 57–75.[abs](see also in 专刊论文推荐:电化学发光体系在生物分析中的最新进展
  4. Zhenqiang Ning, Yongjun Zheng, Deng Pan,Yuanjian Zhang and Yanfei Shen*, Coupling aptazyme and catalytic hairpin assembly for cascaded dual signal amplified electrochemiluminescence biosensing. Biosens. Bioelectron., 2020, 150, 111945. abs (IF: 10.257)
  5. Qing Zhou, Guanghui Li, Kaiyang Chen, Hong Yang, Mengran Yang, Yuye Zhang, Yakun Wan*, Yanfei Shen*, and Yuanjian Zhang*, Simultaneous Unlocking Optoelectronic and Interfacial Properties of C60 for Ultrasensitive Immunosensing by Coupling to Metal−Organic Framework, Anal.Chem., 2020, 92, 983-990. abs (IF: 6.785)
  6. Khishigjargal Ganbat, Deng Pan, Kaiyang Chen, Zhenqiang Ning, Le Xing, Yuanjian Zhang, Yanfei Shen*, One-pot electrografting preparation of bifunctionalized carbon nanotubes for sensitive electrochemical immunosensing, J.Electroanal.Chem. 2020, 863, 113906.Abs (IF: 3.807)
  7. Kaiyang Chen#, Jiyang Xue#,Qing Zhou, Yue Zhang, Mingming Zhang, Yuanjian Zhang, Hai Zhang* and Yanfei Shen*, Coupling Metal-Organic Framework Nanosphere and Nanobody for Boosted Photoelectrochemical Immunoassay of Human Epididymis Protein 4, Anal. Chim. Acta, 2020, 1107, 145. abs (IF: 5.977)

2019

  1. Deng Pan, Kaiyang Chen, Qing Zhou, Jinjin Zhao, Huaijia Xue, Yuanjian Zhang and Yanfei Shen*, Engineering of CdTe/SiO2 nanocomposites: Enhanced signal amplification and biocompatibility for electrochemiluminescent immunoassay of alphafetoprotein. Biosens.Bioelectron. 2019, 131, 178-184. abs (IF: 10.257)
  2. Huaijia Xue, Jinjin Zhao, Qing Zhou, Deng Pan, Yue Zhang, Yuanjian Zhang and Yanfei Shen*, Boosting the Sensitivity of a Photoelectrochemical Immunoassay by Using SiO2@polydopamine Core−Shell Nanoparticles as a Highly Efficient Quencher. ACS Appl.Nano Mater. 2019, 2, 1579-1588. abs
  3. Huaijia Xue, Kaiyang Chen, Qing Zhou, Deng Pan, Yuanjian Zhang and Yanfei Shen, Antimony selenide/graphene oxide composite for sensitive photoelectrochemical detection of DNA methyltransferase activity, J. Mater. Chem. B. 2019, 7*, 6789-6795. abs (IF: 5.344)
  4. Yongjun Zheng, Deng Pan, Yue Zhang, Yuanjian Zhang, Yanfei Shen*, Hemicyanine-based near-infrared fluorescent probe for the ultrasensitive detection of hNQO1 activity and discrimination of human cancer cells. Anal. Chim. Acta, 2019, 1090, 125-132. abs (IF: 5.977)

2018

  1. Qing Zhou, Huaijia Xue, Yuye Zhang, Yanqin Lv, Hongguang Li, Songqin Liu, Yanfei Shen*, and Yuanjian Zhang*, Metal-Free All-Carbon Nanohybrid for Ultrasensitive Photoelectrochemical Immunosensing of alpha-Fetoprotein. ACS Sens. 2018, 3, 1385-1391. abs(IF:7.333)
  2. Huizhen Hu, Deng Pan, Huaijia Xue, Mingming Zhang, Yuanjian Zhang and Yanfei Shen*, A photoelectrochemical immunoassay for tumor necrosis factor-α using a GO-PTCNH2 nanohybrid as a probe. J.Electroanal.Chem. 2018, 824, 195-200. abs (IF:3.807)
  3. Deng Pan, Guanghui Li,Huizhen Hu, Huaijia Xue, Mingming Zhang, Min Zhu, Xue Gong, Yuanjian Zhang, Yakun Wan* and Yanfei Shen*, Direct Immunoassay for Facile and Sensitive Detection of Small Molecule Aflatoxin B1 based on Nanobody. Chem. Eur. J 2018, 24, 9869-9876. abs (IF:4.857)
  4. Mingming Zhang, Guanghui Li, Qing Zhou, Deng Pan, Min Zhu, Runyu Xiao, Yuanjian Zhang, Guoqiu Wu,* Yakun Wan* and Yanfei Shen*, Boosted Electrochemical Immunosensing of Genetically Modified Crop Markers Using Nanobody and Mesoporous Carbon. ACS Sens. 2018, 3, 684. abs (IF:7.333)
  5. Jinjin Zhao, Ning Pan, Fang Huang, Mohanad Aldarouish, Zhifa Wen, Rong Gao, Yuye Zhang, Hong-Ming Hu, Yanfei Shen*, and Li-xin Wang*, Vx3-Functionalized Alumina Nanoparticles Assisted Enrichment of Ubiquitinated Proteins from Cancer Cells for Enhanced Cancer Immunotherapy. Bioconjugate Chem. 2018, 29, 786. abs (IF:4.031)
  6. Yue Zhang, Deng Pan, Qing Zhou, Jinjin Zhao, Ning Pan, Yuanjian Zhang, Li-xin Wang* and Yanfei Shen*,An enzyme cascade-based electrochemical immunoassay using a polydopamine–carbon nanotube nanocomposite for signal amplification. J.Mater.Chem.B 2018, 6, 8180.(IF:5.344)

2017

  1. Yanfei Shen*, Cheng Zhang, Chunguang Yan, Huiqin Chen and Yuanjian Zhang, Fabrication of porous graphitic carbon nitride-titanium dioxide heterojunctions with enhanced photo-energy conversion activity. Chin.Chem.Lett. 2017, 28, 1312.abs (IF:4.632)

2016

  1. Qing Zhou,Guanghui Li, Yuanjian Zhang, Min Zhu, Yakun Wan* and Yanfei Shen*, A Highly Selective and Sensitive Electrochemical Immunoassay of Cry1C UsingNanobody and pi-pi Stacked Graphene Oxide/Thionine Assembly. Anal.Chem. 2016, 88, 9830−9836. abs (1区,Nature Index收录)
  2. Jusheng Lu, Yanfei Shen* and Songqin Liu*,Enhanced light-driven catalytic performance of cytochrome P450 confined in macroporous silica. Chem.Commun.2016, 52, 7703.(IF:6.567)abs (1区,Nature Index收录)
  3. Guanghui Li,Min Zhu,Lu Ma,Junrong Yan,Xiaoling Lu, Yanfei Shen* and Yakun Wan*, Generation of Small Single Domain Nanobody Binders for Sensitive Detection of Testosterone by Electrochemical Impedance Spectroscopy. ACS Appl.Mater.Interfaces 2016, 8, 13830-13839.abs(1区)

2015

  1. Min Zhu, Min Li, Guanghui Li, Zikai Zhou, Hong Liu, Hongtao Lei, Yanfei Shen*, Yakun Wan*, Nanobody-based immunoassay for Bacillus thurineiensis Cry1Ab toxin by detecting the enzymatic formation of polyaniline. Microchim. Acta 2015, 182, 2451–2459. (IF:4.831)abs
  2. Yanfei Shen*, Akinori Saeki , ShuSeki , Jeong-O Lee , Junko Aimi , and Takashi Nakanishi*,Exfoliation of Graphene and Assembly Formation with Alkylated-C60: A Nanocarbon Hybrid towards Photo-Energy Conversion Electrode Devices, Adv.Optical Mater. 2015, 3, 925–930.(IF: 5.188)abs


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