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谢金兵,东南大学首席教授,国家高层次引进人才(火炬计划),智能影像与介入医学国家级重点实验室培育建设点(东南大学)副主任,江苏省“双创人才”跟补资助,南京市紫金山英才,中华医学会放射分会第16届分子影像学组委员。先后留学美国韦恩州立大学化学工程系、日本纳米医药创新中心。具有生命科学、医学影像学、生物医学工程等多学科研究背景,长期从事多功能纳米探针制备及疾病诊疗研究工作。针对临床上对医学影像学新功能和新技术的需求,相继研发了肿瘤多模态分子影像探针、抗体等蛋白类药物递送系统以及智能型纳米递送体系,用于高效穿透血脑屏障进行阿尔兹海默症及肿瘤等疾病的精准诊疗。近年来,在国际顶级期刊 Nature Nanotechnology、Chemical Society Reviews、Nature Biomedical Engineering、Nature Comm.、Advanced Materials、ACS Nano等发表论文40多篇,研究成果被多家媒体作为亮点专题报道和评述。先后获得科技部火炬计划,国家自然科学基金面上、青年项目,日本学术振兴会(JSPS)特别研究员等资助。应邀担任 Scientific Reports等杂志编辑,长期担任 ACS Nano,Biomaterials, Theranostics 等多个国际学术期刊审稿人。
本课题组长期招聘有编制青年教师(讲师,副研究员,副教授等),师资博士后,欢迎申报;
热烈欢迎具有医学、生物学、药学、生物材料、或化学合成等任一相关背景的同学申报本课题组 硕士、博士研究生。
近5年代表性文章
15. Open-Source Throttling of CD8+ T Cells in Brain with Low-Intensity Focused Ultrasound-Guided Sequential Delivery of CXCL10, IL-2, and aPD-L1 for Glioblastoma Immunotherapy. Advanced Materials 2024, adma.202407235;(If=27.4,通讯作者)
14. Protein nanoparticles as drug delivery systems for cancer theranostics. Journal of Controlled Release 2024,371, 429-444;(If=10.8,通讯作者)
13. Zwitterionic micelles efficiently deliver oral insulin without opening tight junctions. Nature Nanotechnology 2020,15,605-614; (If=40.523,共同一作)
12. Recent Advances in Biomaterials-boosted Adoptive Cell Therapy. Chemical Society Reviews 2022, DOI: 10.1039/d1cs00786f; (IF=60.615,通讯作者)
11. Dual-sensitive Fab-encapsulated glucosylated nanocarrier for crossing the BBB and reducing amyloid beta plaques in Alzheimer’s disease mouse. ACS Nano 2020, 14,6729-6742; (If=18.027,第一作者)
10. Recruiting T cells towards brain for enhanced glioblastoma immunotherapeutic efficacy by co-delivery of cytokines and immune checkpoint antibodies with macrophage membrane-camouflaged nano vesicles. Advanced Materials 2023, adma.202209785; (If=32.086,通讯作者)
9. Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitorsand chemotherapeutic agents for glioblastoma therapy
Nature Communications, 2024, 15,1118(IF=17.694, 通讯作者).
8. Micelles with ultralow critical micelle concentration as carriers for drug delivery, Nature Biomedical Engineering 2018, 2, 318-325;(If=29.234)
7. Conjugation of glucosylated polymer chains to checkpoint blockade antibodies augments their efficacy and specificity for glioblastoma. Nature Biomedical Engineering 2021,5,1274-1287; (If=29.234)
6. Nanomaterial-based blood-Brain-Barrier (BBB) crossing strategies. Biomaterials 2019, 224, 119491; (If=15.304,第一作者)
5. Targeted dual-siRNA delivery via non-viral polymeric vectors for idiopathic pulmonary fibrosis therapy. Advanced Materials 2021, 33,2007798; (If=32.086,通讯作者)
4. Co-delivery dual-siRNA of PTPN13 and NOX4 via myofibroblast-targeting polymeric micelles for idiopathic pulmonary fibrosis therapy. Theranostics 2021,11,3244-3261; (If=11.6,通讯作者)
3. Size-Changeable Nanoprobes for the Combined Radiotherapy and Photodynamic Therapy of Triple-Negative Breast Cancer. European Journal of Nuclear Medicine and Molecular Imaging 2022, doi.org/10.1007/s00259-022-05830-9;(IF=10.057,通讯作者)
2. Photo-inducible protein-inorganic nanoparticle assembly for active targeted tumor theranostics. Nanoscale 2019,11,6136-6144; (IF=8.307,第一作者)
1. Simple Protein Modification Using Zwitterionic Polymer to Mitigate the bioactivity Loss of Conjugated Insulin, Advanced Healthcare Materials 2017, 6, 1601428, (IF=11.092,第一作者)
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