主持或参与基金项目：

(1) 国家自然科学基金委员会, 青年科学基金项目, 81802526, APMAP在前列腺癌上皮间质转化中的作用及机制研究, 2019-01-01 至 2021-12-31, 21万元, 结题, 主持

(2) 中国科学院苏州生物医学工程技术研究所, 基础科研, E0550112, 细胞脂筏区域LncRNA的组成与功能研究, 2020-01 至 2021-06, 5万元, 结题, 主持

(3) 中国科学院, 应用研究, YJKYYQ20180032, 双通道外泌体颗粒示踪分析仪研制, 2019-01 至 2020-12,300万元, 结题, 参与

(4) 中国博士后科学基金会, 基础研究, 2018M642321, 胆固醇相关的Lncrna调控网络在肿瘤中的作用机制, 2018-11 至 2020-12, 5万元, 结题, 主持

(5) 中国科学院苏州生物医学工程技术研究所, 基础科研, Y9510101, Vitamin D受体通过调控Wnt/β-catenin信号通路抑制结直肠癌细胞侵袭及转移机制研究 , 2019-08 至 2020-08, 10万元, 结题, 主持

(6) 中国科学院苏州生物医学工程技术研究所, 基础研究, Y811531101, 癌细胞外泌体检测技术及其相关分子生物标志物临床应用的研究, 2018-07 至 2020-07, 20万元, 结题, 主持

(7) 江苏省科学技术厅, 基础研究计划, BK20160174, 膳食脂质促进前列腺癌侵袭转移的作用与机制研究,2016-07 至 2019-06, 20万元, 结题, 主持

代表性论著：

(1) Siyuan Jiang; Xiaoqi Han; Tihui Liu; Ying He; Zidong Zhao; Tongfeng Liu; Shuwen Cheng;Jihang Zhang; Liqiang Duan; Yajuan Liu; Tianyou Cheng; Yong Liu; Qinong Ye; Shan Gao ; HUNKinhibits cargo uptake and lysosomal traffic in the caveolar pathway via the AGAP3/ARF6. Science Bulletin, 2023, 69(2): 173-178

(2) Siyuan Jiang; Xiaoqi Han; Zidong Zhao; Dalong Song; Shuwen Cheng; Tihui Liu; Xujie Zhao;Yinmin Gu; Liqiang Duan; Shan Gao ; Hypoxia inhibits HUNK kinase activity to induce epithelialmesenchymal transition. Biochemical and Biophysical Research Communications, 2023, 681(12): 271-275

 (3)  Siyuan Jiang, Xuetong Wang, Dalong Song, XiaoJun Liu, Yinmin Gu, Zhiyuan Xu, Xiaodong Wang, Xiaolu Zhang, Qinong Ye, Zhou Tong, BingXue Yan, Jie Yu, Yunzhao Chen, Minxuan Sun, Yang Wang, Shan Gao.  Cholesterol Induces Epithelial-to-Mesenchymal Transition of Prostate Cancer Cells by Suppressing Degradation of EGFR through APMAP, Cancer Res, 2019,79(12): 3063-3075 

(4) Siyuan Jiang#; Lianfang Zhao#; Yilu Lu#; Meiling Wang; Chen Yuan; Dachang Tao; Yunqiang Liu;Huaqin Sun; Sizong Zhang; Yongxin Ma; Piwil2 inhibits keratin 8 degradationthrough promoting p38-induced phosphorylation to resist Fas-mediated apoptosis., Molecular and Cellular Biology, 2014, 34(21): 3928-3938

(5) Xiaoqi Han; Siyuan Jiang; Yinmin Gu; Lihua Ding; Enhao Zhao; Dongxing Cao; Xiaodong Wang;Ya Wen; Yongbo Pan; Xin Yan; Liqiang Duan; Minxuan Sun; Tao Zhou; Yajuan Liu; Hongbo Hu; QinongYe; Shan Gao ; HUNK inhibits epithelial-mesenchymal transition of CRC via direct phosphorylationof GEF-H1 and activating RhoA/LIMK-1/CFL-1. Cell Death & Disease, 2023, 14(5)

(6) Xiwang Yang#, Ya Wen#, Shaomin Liu, Liqiang Duan, Tongfeng Liu, Zhou Tong, Zhuo Wang, Yinmin Gu, Yibo Xi, Xiaodong Wang, Dingsan Luo, Ruobing Zhang, Yajuan Liu, Yang Wang, Tianyou Cheng, Siyuan Jiang, Xiaofeng Zhu, Xiaohui Yang, Yongbo Pan, Shuwen Cheng, Qinong Ye, Jinfei Chen, Xiaoding Xu, Shan Gao. LCDR regulates the integrity of lysosomal membrane by hnRNP K-stabilized LAPTM5 transcript and promotes cell survival. Proc Natl Acad Sci USA, 2022 Feb 1;119(5). 

(7) Xiaodong Wang#, Xiaohui Yang#, Chang Zhang, Yang Wang, Tianyou Cheng, Liqiang Duan, Zhou Tong, Shuguang Tan, Hangjie Zhang, Phei Er Saw, Yinmin Gu, Jinhua Wang, Yibi Zhang, Lina Shang, Yajuan Liu, Siyuan Jiang, Bingxue Yan, Rong Li, Yue Yang, Jie Yu, Yunzhao Chen, George Fu Gao, Qinong Ye, Shan Gao. Tumor cell-intrinsic PD-1 receptor is a tumor suppressor and mediates resistance to PD-1 blockade therapy. Proc Natl Acad Sci USA, 2020 Mar 24;117(12).

(8) Yinmin Gu#, Shaoxi Niu#, Yang Wang, Liqiang Duan, Yongbo Pan, Zhou Tong, Xu Zhang, Zhenyu Yang, Bo Peng, Xiaodong Wang, Xiaoqi Han, Yuxin Li, Tianyou Cheng, Yajuan Liu, Lina Shang, Tongfeng Liu, Xiwang Yang, Minxuan Sun, Siyuan Jiang, Chang Zhang, Ning Zhang, Qinong Ye, Shan Gao. DMDRMR-Mediated Regulation of m6A-Modified CDK4 by m6A Reader IGF2BP3 Drives ccRCC Progression. Cancer Res, 2021 Feb 15;81(4):923-934. 

 专利：

(1) 蒋思远; 高山 ; 一种癌症标志物及其用途, 2019-9-10, 中国, ZL201811069185.6

 (2) 高山; 蒋思远 ; 生物标志物及应用, 2021-1-15, 中国, ZL202010181008.8