1.国家自然科学基金面上项目，智力障碍风险基因LRRC7突变所致早期生长激素缺乏的机制研究，负责人，50万，2026.01-2029.12 

2. 国家自然科学基金面上项目，FGFR2调控PV/SST抑制性突触发育的机制及其应用研究，负责人，58万，2022.01-2025.12. 

3. 科技创新2030-脑科学与类脑研究重大项目，脑智异常的脑白质发育机制，课题骨干，承担经费125万，2021.12-2026.11.

4. 国家自然科学基金面上项目, ErbB受体的广谱性配体HB-EGF特异性调控中枢局域性髓鞘发育的机制研究， 负责人，59万, 2019.01-2022.12. 

5. 国家自然科学基金面上项目，自闭症关联突触蛋白Densin-180的致病机理研究，负责人，62万，2017.01-2020.12. 

6. 国家自然科学基金面上项目，ErbB信号通路调节精神分裂症病理病症发生的髓鞘机制研究，负责人，97万，2014.01-2017.12. 

7. 国家自然科学基金面上项目，中枢髓鞘晚期发育的关键分子机制及其与精神性疾病相关性的研究，负责人，15万，2012.01-2012.12. 

8. 杭州市高层次留学回国人员在杭创新项目，局域性白质损伤与精神分裂症病理病症发生机制的研究，负责人，15万，2016.01-2018.12.

主要发表论文： (*, correspondence or co-correspondence. # , equal contributing first author. ) 

1.    Z. Wei#, S. Zhang#, K. Bai#, Y. Liu#, Y. Luan, Z. Hu, Y. Li, Z. Qu,X. Hu, X. Ding, W. Liang, H. Li, H. He*, Y. Tao*. Distinct FGF-FGFR sets regulate inhibitory presynapticdifferentiation from parvalbumin- and somatostatin-positive interneurons. Development152(13):dev204532. doi: 10.1242/dev.204532, 2025.

(当期重点推荐： Research Highlight “FGF-FGFR combinationscontrol inhibitory synapses”.      

人物专访“The people behind the papers -Yanmei Tao and Zhengdong Wei”）

2.     X. Hu, Q. Zhu, T. Lou, Q. Hu, H. Li, Y. Xu, X.Niu, L. He, H. Huang, M.Qiu,Y. Shen, J.-M. Jia, Y. Tao*. Pan-ErbBinhibition impairs cognition via disrupting myelination andaerobic glycolysis in oligodendrocytes. Proc. Natl.Acad. Sci. U. S. A. 121(45), e2405152121. doi.org/10.1073/pnas.2405152121, 2024.

 (PNAS专文评述: “Revisitingthe role of ErbBs in oligodendrocyte development.” doi: 10.1073/pnas.2422181121）

3.    X. Hu#, G. Xiao#, L. He#, X. Niu, H. Li, T. Lou, Q.Hu, Y.Yang, Q.Xu, Z.Wei, M.Qiu, K.F. Tanaka, Y.Shen, Y. Tao*.SustainedErbB activation causes demyelination and hypomyelination by driving necroptosisof mature oligodendrocytes and apoptosis of oligodendrocyte precursor cells.  Journalof Neuroscience  41 (48) 9872-9890,2021.  doi:10.1523/JNEUROSCI.2922-20.2021.

（Featured article, 受到“This week in The Journal”版块重点推荐）

4.    X. Hu#, G. Xiao#, L. He#, Q. Zhu, X. Niu, H. Li, Q. Xu,Z. Wei, H. Huang, Y. Luan, M. Qiu, K. F. Tanaka, Y. Shen, Y. Tao*. ErbB dysregulation impairs cognition viamyelination-dependent and - independent oligodendropathy. BioRxiv, doi: 10.1101/2020.09.09.289223, 2020.

5.    G. Xiao#, H. Li#, X. Hu, X. Niu, Q. Xu, Y. Tao*. Interference of commissural connections through thegenu of the corpus callosum specifically impairs sensorimotor gating. BehaviouralBrain Research, 411, 113383, 2021.

6.    Z.-Y. Luo, L. Huang, S. Lin, Y.-N. Yin, W. Jie, N.-Y.Hu, Y.-Y. Hu, Y.-F. Guan, J.-H. Liu, Q.-L. You, Y.-H. Chen, Z.-C. Luo, S.-R.Zhang, X.-W. Li, J.-M. Yang, Y. Tao,L. Mei, T.-M. Gao*, Erbin in Amygdala Parvalbumin-Positive NeuronsModulates Anxiety-like Behaviors. Biological Psychiatry 87(10):926-936,2019.

7.    X. Ge#, G. Xiao#,H. Huang, J. Du, Y. Tao, A.Yang, H. Wu, Z. Zhang, M. Qiu*. Stage-dependent regulation of oligodendrocytedevelopment and enhancement of myelin repair by dominant negative Master-mind 1protein. Glia, 67(9):1654-1666, 2019.

8.    J.Chen, W. He, X. Hu, Y. Shen, J. Cao, Z. Wei, Y. Luan, L. He, F. Jiang, and Y. Tao*, Arole for ErbB signaling in the induction of reactive astrogliosis. Cell Discovery  3:17044, 2017.

9.    Y. Tao#, C. Shen#, S. Luo#, W. Traore, S. Marchetto, M.-J.Santoni, L. Xu, C. Shi, J. Mei, R. Bates, X. Liu, K. Zhao, W.-C. Xiong, J.-P.Borg, L. Mei*, Role of Erbin in ErbB2-dependent breast tumor growth. Proc. Natl.Acad. Sci. U. S. A. doi/10.1073/pnas.1407139111, 2014.

10.  Y. Tao, W.-C. Xiong, L. Mei*，Erbin in cortical inhibition. Future Neurology, 8(4): 369-372. doi: 10.2217/fnl.13.18, 2013.

11.  Y. Tao*,Isolation and culture of Schwann cells. Neural Development: Methods in MolecularBiology, Vol 1018: 93-104, 2013. (著作)

12. Y. Tao#,Y. Chen#, C. Shen#,Z. Luo, C.R. Bates, D. Lee, S. Marchetto, T. Gao, J. P. Borg, W. -C. Xiong, L.Mei*. Erbin interacts with TARP g-2 for surface expression of AMPA receptorsin cortical interneurons. Nature Neuroscience 16(3):290-9.doi: 10.1038/nn.3320, 2013.

13. C.Liang#, Y. Tao*#, C.Shen, W. -C. Xiong, L. Mei*. Erbin is required for axon regeneration andremyelination after nerve injury in adulthood. Journal of Neuroscience  32(43):15169-15180, 2012.

14. A. Ting, Y. Chen, L.Wen, D.-M. Yin, C. Shen, Y. Tao, X. Liu, W.-C. Xiong, L.Mei*. Neuregulin1 promotes excitatory synapse development and function inGABAergic interneurons. Journal of Neuroscience 31(1):15-25, 2011.

15.  Y.Tao, P. Dai, Y. Liu,W. -C. Xiong, J. P. Borg, L. Mei*.  Erbinregulates neuregulin signaling and myelination. Proc.Natl. Acad. Sci. U. S. A. 106(23):9477-9482, 2009. 

( FACULTY OF 1000 BIOLOGY重点推荐)

16. S.Luo, B.Zhang, X.P. Dong, Y. Tao,A. Ting, Z. Zhou, J. Meixiong, J. Luo, F.C. Chiu, W. -C. Xiong, L. Mei*.  HSP90beta regulates rapsyn turnover and subsequent AChR cluster formation andmaintenance. Neuron 60(1):97-110, 2008.

17. J. Arikkath, I. Israely, Y. Tao, L. Mei, X. Liu, L. F.Reichardt*.  Erbin controls dendriticmorphogenesis by regulating localization of delta-Catenin. Journal of Neuroscience 28(28), 7047-7056,2008.

18. C. Brooks, Q. Wei, L. Feng, G.Dong, Y. Tao, L. Mei, Z.-J. Xie, D. C Chan, Z. Dong*.  Bak regulates mitochondrial morphology andpathology during apoptosis by interacting with Mitofusins. Proc. Natl. Acad. Sci. U. S.A.  104(28):11649-11654, 2007.

19.  R.-S. Woo#,X.M. Li#, Y. Tao, E Carpenter-Hyland, J. Wu, C. Lai,W.-C. Xiong, and L. Mei*.  Neuregulin-1Enhances Depolarization-Induced GABA Release. Neuron 54(4):599-610,2007.

20.  Y. Liu, Y.Tao, R.-S. Woo, W.-C. Xiong, and Lin Mei*. Stimulated ErbB4internalization is necessary for neuregulin signaling in neurons. Biochemical and Biophysical ResearchCommunications 354(2):505-510, 2007.

21.  Y.Tao#, D. Yan#, Q. Yang, R. Zeng, Y.Wang*.  Low K+ promotes NF-κB/DNA binding in neuronal apoptosisinduced by K+ loss. Molecularand Cellular Biology 26(3):1038-1050, 2006. #, equal contributing first author.

22.  Y. Tao#, R. Zeng#, B. Shen#,J. Jia, Y. Wang*.  Neuronal transmissionstimulates the phosphorylation of Kv1.4 channel at Ser229 through proteinkinase A. Journal of Neurochemistry 94(6):1512-1522, 2005. #, equal contributing first author.

23.  Y. Tao*,W. Dong, S. Jia, X. Dai.  Effect ofginkgo biloba extract (EGb761) on the changes of intracellular calciumconcentration and mobility induced by amikacin in outer hair cell isolated fromguinea pig cochlear. Chinese Journalof Pharmacology and Toxicology, 15(5):372-376,2001.

24. Y. Tao*, J. Wu, Y. Wang, Z. Zhang,J. Wang, Z. Hu.  Effects of low levellaser irradiation on intracellular free calcium concentration and SOD activity invitro and in vivo study. AppliedLaser, 17(2):89-93,1997.

2008.03，佐治亚-南卡罗来纳州神经科学联合研讨会。地点：南卡罗来纳州哥伦比亚；题目：Stabilization of ErbB2 by Erbin is essential for neuregulin regulation on myelination of PNS. 

2009.10，全美儿童疾病神经生物学研讨会及第38届儿童神经学会年会。地点：肯塔基州路易斯维尔；题目：Erbin regulates neuregulin signaling and myelination. 

2013.09，第10届中国神经科学学会双年会。地点：北京；题目：Regulation of excitatory synapse transmission in interneurons. 

2014.04，中国细胞学会神经细胞生物学分会第四届第四届神经细胞生物学前沿研讨会。地点：南昌；题目：Cell-specific roles of ErbB signaling in neurons and glia. 

2015.05 ， 冷泉港亚洲会议 “NOVEL INSIGHTS INTO GLIA FUNCTION & DYSFUNCTION”。地点：苏州；题目：Tyrosine kinase receptor ErbB signaling activates resident astrocytes for astrogliosis. 

2015.11，第六届世界基因产业大会。地点：青岛；题目：Role of Erbin in ErbB2-Dependent Breast Tumor Growth. 注：“分子细胞分会 I” 共同主持人。 

2016.06，第四届浙江省神经科学学会。地点：金华；题目：Regulation of central myelination in adolescent brain by ErbB signaling. 

2018.07，第十届海内外华人神经科学家研讨会。地点：青岛；题目：Molecular regulation of astrogliosis. 

2019.12，第一届髓鞘机制与相关疾病国际论坛。地点：杭州；题目：ErbB receptor dysregulation induces multiple types of oligodendropathy in a differentiation stage-specific manner. 注：会议共同组织者。

2024. 09， 中国神经科学学会第17届全国学术会议。地点：苏州；题目：Neuronal HB-EGF specifically regulates myelin development of the sensory callosal pathway.