【蔡彦导师】招生“生物科学与医学工程学院”研究生介绍

更新于 2022-03-14 导师主页
蔡彦 副研究员 硕士生导师
生物科学与医学工程学院
生物医学工程
生物力学,生物数学建模,数值模拟计算
yancai@seu.edu.cn

蔡彦,女,籍贯安徽。博士、副研究员、硕士生导师。中国微循环学会第一届学术委员。东南大学首批“至善青年学者”。

1、教育背景;

2006年毕业于中山大学理论与应用力学系,本科;

2011年毕业于复旦大学力学系生物力学专业,博士,期间经由国家公派联合培养于英国布鲁内尔大学生物工程研究所学习。

2、研究方向;

(1)微循环血流动力学数值模拟;

(2)动脉粥样斑块微环境变化的研究;

(3)肺气道三维重建及流体动力学计算。

每年拟招收1-2名硕士研究生,欢迎具有生物医学工程、力学、医学相关专业背景的同学报考


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科研项目

1)     National Nature Science Foundation of China No. 12072074 (PI)     01/2021-12/2024

The role of VSMC phenotypic switching in the anti-inflammatory therapy of atherosclerotic plaque: coupled modeling of microenvironmental factors

2)     National Nature Science Foundation of China No. 11302050 (PI)     01/2014-12/2016

The influence of normalization of tumor microenvironment on the chemotherapeutic drug delivery in non-small cell lung cancer

3)     Nature Science Foundation of Jiangsu Province No. BK20130593 (PI) 07/2013-07/2016

Multiscale mathematical modeling for hypoxic microenvironment in solid tumors


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研究成果

[1] Muyi Guo#, Yan Cai#, Chunliu He, Zhiyong Li*. Coupled modeling of lipid deposition, inflammatory response and intraplaque angiogenesis in atherosclerotic plaque. Annals of Biomedical Engineering, 2019;47(2):439-452.

[2] Muyi Guo#, Yan Cai#, Xinke Yao, Zhiyong Li*. Mathematical modeling of atherosclerotic plaque destabilization: Role of neovascularization and intraplaque hemorrhage. Journal of Theoretical Biology, 2018, 450: 53-65.

[3] Pan SY#, Ding M#, Huang J, Cai Y*, Huang YZ*. Airway resistance variation correlates with prognosis of critically ill COVID-19 patients: A computational fluid dynamics study. Comput Methods Programs Biomed. 2021 Jun 25;208:106257.

[4] Pan J#, Cai Y#, Liu M, Li Z*. Role of vascular smooth muscle cell phenotypic switching in plaque progression: A hybrid modeling study. J Theor Biol. 2021 Oct 7;526:110794.

[5] Pan J#, Cai Y#, Wang L, Maehara A, Mintz GS, Tang D, Li Z*. A prediction tool for plaque progression based on patient-specific multi-physical modeling. PLoS Comput Biol. 2021 Mar 29;17(3):e1008344.


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