科研项目

1.     Shanglin Gu, Li Lv, Xue Lin, Xingyu Li, JunchengDai, Jianqiong Zhang, Ren Kong, Wei Xie, Jian Li（Corresponding author）,Using structural analysis to explore the role ofhepatitis B virus mutations in immune escape from liver cancer in Chinese,European and American populations, Journal of Biomolecular & Dyanmics,2020, Accepted.

2.     Jian Li （Co-corresponding author）, Xue Lin,Mingya Wang, Yunyun Hu, Kaiyu Xue, Shuanglin Gu, Li Lv, Saijun Huang, Wei Xie,Potential Role of Genomic Imprinted Genes and Brain Developmental Related Genesin Autism, BMC Medical Genomics, 2020, Mar 26;13(1):54

3.     Mingliang Tang, Jian Li (Co-firstauthors), Li He, Rongrong Guo, Xiaoqian Yan, Dan Li, YuhuaZhang, Menghui Liao, Buwei Shao, Yangnan Hu, Yun Liu, Qilin Tang, Lin Xia, XingGuo, Renjie Chai, Transcriptomic profiling of neural stem cell differentiationon graphene substrates. Colloids Surf BBiointerfaces. 2019 Jun 25;182:110324. doi: 10.1016/j.colsurfb.2019.06.054. IF: 4.11

4.     Yuzhi Wang, Xue Lin, Xue Gong, Lele Wu, Jun Zhang,Weiguang Liu, Jian Li, Liming Chen. Atypical GATA transcription factorTRPS1 represses gene expression by recruiting CHD4/NuRD(MTA2) and suppressescell migration and invasion by repressing TP63 expression. Oncogenesis. 2018 Dec 19;7(12):96. doi:10.1038/s41389-018-0108-9. IF: 4.692

5.     Yan Liu, Jian Li (Co-first authors),Zhifang Ma, Jun Zhang, Yuzhi Wang, Zhenghong Yu, Xue Lin, Li An, Huilin Zheng,Shuang Yu, Jingzhong Zhang, Zhi Xu, Liming Chen. Oncogenic functions of ProteinKinase D2 and D3 in regulating multiple cancer-related pathways and breastcancer. Cancer Medicine, 2019, 8:729–741.. IF:3.202

6.    Jing Zuo, Jian Li (Co-first author, co-corresponding author), Rongxin Zhang,Longsheng Xu, Hanhan Chen, Xiaohuan Jia, Zhipeng Su, Linhong Zhao, Xing Huang,Wei Xie, Institute Collection and Analysis ofNanobodies (iCAN): a comprehensive database and analysis platform fornanobodies. BMC Genomics (2017), 18(1):797. doi:10.1186/s12864-017-4204-6. IF: 3.99

7.    Liu Yan, Jian Li (Co-first authors),Jun Zhang, Zhenghong Yu, Shiyi Yu, Lele Wu, Yuzhi Wang, Xue Gong, Chenxi Wu,Xiuxiu Cai, Lin Mo, Mingya Wang, Jun Gu, Liming Chen. Oncogenic protein kinaseD3 regulating networks in invasive breast cancer. International Journal ofBiological Sciences, 2017, 13(6): 748-758. IF:4.057

8.     Yu Xue,Eric-Wubbo Lameijer, Kai Ye, Kunlin Zhang, Suhua Chang, Xiaoyue Wang, JianminWu, Ge Gao, Fangqing Zhao, Jian Li, Chunsheng Han,Shuhua Xu, Jingfa Xiao, Xuerui Yang, Xiaomin Ying, Xuegong Zhang, Wei-Hua Chen,Yun Liu, Zhang Zhang, Kun Huang, Jun Yu. Precision Medicine: What ChallengesAre We Facing? Genomics Proteomics Bioinformatics 14 (2016) 253–261. IF: 6.615

9.     AndersPatrik Gunnarsson, Rikke Christensen, Jian Li, Uffe Birk Jensen.Global gene expression and comparison between multiple populations in the mouseepidermis. Stem Cell Res. 2016 Jul; 17(1):191-202. IF: 4.956

10.  Anders PatrikGunnarsson,Rikke Christensen,Jian Li, Uffe Birk Jensen,Dataset on gene expression profiling ofmultiple murine hair follicle populations, Data in Brief, 2016, 9, 328-34,PMID: 27672671, PMCID: PMC5030336, DOI:10.1016/j.dib.2016.08.063.

11.  XueLin, Jan Stenvang, Mads Kristoffer Heilskov Rasmussen, Shida Zhu, GuangxiaYang, Kirstine Belling, Claus Lindbjerg Andersen*, Jian Li*, LarsBolund*, Nils Brünner*. The Potential Role of Alu Y in the Development ofResistance to SN38 (Irinotecan) and Oxaliplatin in Colon Cancer. BMC Genomics,2015, 16:404.(*corresponding author). IF: 3.99

12.  XueLin, JianLi (co-first author), Guangling Yin, Qian Zhao, Daniel Elias, AnneLykkesfeldt, Jan Stenvang, Nils Brünner, Jun Wang, Huanming Yang, Lars Bolund,Henrik J. Ditzel: Integrative Analyses of Gene Expression and DNA MethylationProfiles in A Breast Cancer Cell Line Model of Tamoxifen-Resistance Indicate ACrucial Role of Cells with Stem-like Properties. Breast Cancer Res. 2013 Dec19;15(6):R119. IF: 6.142

13.  Jian Li, XueLin, Nils Brunner, Lars Bolund, Huanming Yang: Novel methods in the study ofthe breast cancer genome: towards a better understanding of the breast cancerdisease. Journal of Cancer Therapy, 2012, 3, 797-809. IF: 0.52

14. Jian Li, Kai Wang, Fei Gao, Thomas D Jensen, Shengting Li, PM DeAngelis, SKølvraa, C Proby, O Forslund, Lars Bolund, OPF Clausen (2012): Arraycomparative genomic hybridization of keratoacanthomas and squamous cellcarcinomas: Different patterns of genetic aberrations and different recurrentaberrations suggest two distinct entities. J Invest Dermatol, 2012 Aug;132(8):2060-6. doi:10.1038/jid.2012.104. Epub 2012 Apr 26. IF: 7.216

15. Jian Li, Qian Zhao, Lars Bolund (2011): Computational methods for epigeneticanalysis -the protocol of computational analysis for modifiedmethylation-specific digital karyotyping (MMSDK) based on massively parallelsequencing. Methods Mol Biol, 791:313-28.

16. Steffen Durinck, Christine Ho, Nicholas J.Wang, Wilson Liao, Lakshmi R. Jakkula, Eric A. Collisson, Jennifer Pons,Sai-Wing Chan, Ernest T. Lam, Catherine Chu, Kyunghee Park, Sung-woo Hong, JoeS. Hur, Nam Huh, Isaac M. Neuhaus, Siegrid S. Yu, Roy T. Grekin, Theodora M.Mauro, James E. Cleaver, Pui-Yan Kwok, Philip E. Leboit, Gad Getz, KristianCibulskis, Jon C. Aster, Haiyan Huang, Elizabeth Purdom, Jian Li, LarsBolund, Sarah T. Arron, Joe W. Gray, Paul Spellman, Raymond J. Cho (2011):Temporal dissection of tumorigenesis in primary cancers. Cancer Discovery,1:137. IF: 19.453

17. Fei Gao, Yonglun Luo, Shengting Li, JianLi, Lin Lin, Anders Lade Nielsen, Charlotte Brandt Sørensen, JunWang, Xiuqing Zhang,Yutao Du, Huanming Yang, Lars Bolund (2011): Genome-wide DNA methylation andgene expression differences in liver and muscle of phenotypically normal clonedpigs and naturally bred controls. PLoS ONE, 6(10):e25901. Epub 2011 Oct 11. IF: 3.234

18. Fei Gao, Shengting Li, Lin Lin, JianLi, Yonglun Luo, Xiuqing Zhang, Anders Lade Nielsen, Lars Bolund(2011): DNA methylation in peripheral blood cells of pigs cloned by somaticcell nuclear transfer. Cell Reprogram, 13:307. IF: 1.788

19. Thomas D. Jensen, Jian Li, Kai Wang,Jan Lindebjerg, Steen Kølvraa, Lars Bolund, Anders Jakobsen, Gert B. Petersen,Shengting Li, Dorthe G. Crüger (2011): Identification of chromosome aberrationsin sporadic microsatellite stable and instable colorectal cancers usingarray-based comparative genomic hybridization. Cancer Genetics, 204: 84. IF: 2.417

20. Jian Li, KaiWang, Thomas Dyrso Jensen, Lars Bolund, Carsten Wiuf. (2010): Tumorheterogeneity in neoplasms of breast, colon, and skin. BMC Research Notes,3:321.

21. Kai Wang, Jian Li, ShengtingLi, Lars Bolund, Carsten Wiuf. (2009): Estimation of tumor heterogeneity usingCGH array data. BMC Bioinformatics, 10 (1):12. IF: 2.58

22. Jian Li, FeiGao, Ning Li, Shengting Li, Kai Wang, Geng Tian, Shangang Jia, Guangliang Yin,Xiuqing Zhang, Huanming Yang, Anders Lade Nielsen and Lars Bolund, (2009): Animproved method for genome wide DNA methylation profiling correlated totranscription and genomic instability in two breast cancer cell lines. BMCGenomics, 13; 10:223. IF: 3.99

23. Jian Li, KaiWang, Shengting Li, Vera Timmermans-Wielenga, Fritz Rank, Carsten Wiuf, XiuqingZhang, Huanming Yang and Lars Bolund, (2009): DNA copy number aberrations in breastcancer studied by array comparative genomic hybridization. Genomics, Proteomics& Bioinformatics, 7(1-2): 13-24. IF:6.615

24. Jian Li, PavelGromov, Irina Gromova, José M. Moreira, Vera Timmermans-Wielenga, Fritz Rank,Kai Wang, Shengting Li, Heng Li, Carsten Wiuf, Huanming Yang, Xiuqing Zhang,Lars Bolund and Julio E. Celis, (2008): Omics-based profiling of carcinoma ofthe breast and regional lymph node metastasis. Proteomics, 8: 5038-5052. IF: 4.132